Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo

This study reports on what we believe are novel mechanism(s) of the vascular protective action of adiponectin. We used intravital microscopy to measure leukocyte-endothelium interactions in adiponectin-deficient (Ad(-/-)) mice and found that adiponectin deficiency was associated with a 2-fold increa...

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Veröffentlicht in:The Journal of clinical investigation 2007-06, Vol.117 (6), p.1718-1726
Hauptverfasser: Ouedraogo, Raogo, Gong, Yulan, Berzins, Brett, Wu, Xiandong, Mahadev, Kalyankar, Hough, Kelly, Chan, Lawrence, Goldstein, Barry J, Scalia, Rosario
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Sprache:eng
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