Transition from Squamous Cell Carcinoma to Adenocarcinoma in Adenosquamous Carcinoma of the Lung

The heterogeneity of tumor cells is frequently observed in lung cancer, but the clonality of these cells has not yet been established. The distinct components of 12 lung adenosquamous carcinomas were compared by genetic alterations of p53 and K-ras, chromosomal abnormalities at 9p21 and 9q31–32, and...

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Veröffentlicht in:	The American journal of pathology 2000-04, Vol.156 (4), p.1289-1298
Hauptverfasser:	Kanazawa, Hironobu, Ebina, Masahito, Ino-oka, Nozomu, Shimizukawa, Minoru, Takahashi, Toru, Fujimura, Shigefumi, Imai, Tadashi, Nukiwa, Toshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Aged Biological and medical sciences Carcinoma, Adenosquamous - genetics Carcinoma, Adenosquamous - metabolism Carcinoma, Adenosquamous - pathology Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Chromosomes, Human, Pair 9 - genetics Female Genes, ras - genetics Humans Immunohistochemistry Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Medical sciences Microsatellite Repeats Middle Aged Mutation Pneumology Regular Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Tumors of the respiratory system and mediastinum
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