Population pharmacokinetics of ondansetron: a covariate analysis

Aims To construct a population model to account for the variability in ondansetron pharmacokinetics and to evaluate methods for the efficient development of population models. Methods Population models were developed using 99 subjects consisting of paediatric patients, young, elderly and aged volu...

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Veröffentlicht in:	British journal of clinical pharmacology 1998-08, Vol.46 (2), p.117-125
Hauptverfasser:	De Alwis, D. P., Aarons, L., Palmer, J. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Analysis of Variance Antiemetics - pharmacokinetics Biological and medical sciences Child Child, Preschool covariate analysis Demography Digestive system Female Humans Male Medical sciences Metabolic Clearance Rate Middle Aged Models, Statistical NONMEM ondansetron Ondansetron - pharmacokinetics Original Pharmacology. Drug treatments population pharmacokinetics
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