Guidelines on the management of osteoporosis associated with chronic liver disease
Peak bone mass is determined by genetic factors, hormonal status, diet, and exercise, and men have a higher peak bone mass than women. [...]irrespective of other factors, the incidence of osteoporosis increases in the elderly as age related bone loss is a normal phenomenon. Current research requirem...
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| Veröffentlicht in: | Gut 2002-02, Vol.50 (suppl 1), p.i1-9 |
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| creator | Collier, J D Ninkovic, M Compston, J E |
| description | Peak bone mass is determined by genetic factors, hormonal status, diet, and exercise, and men have a higher peak bone mass than women. [...]irrespective of other factors, the incidence of osteoporosis increases in the elderly as age related bone loss is a normal phenomenon. Current research requirements include: a prospective study of the prevalence of fractures in patients with chronic liver disease; a study of the prevalence of osteoporosis in patients with all stages of PBC compared with sex and age matched controls; a prospective study of the prevalence of hypogonadism in males with cirrhosis with and without osteoporosis; assessment of the safety of restoring testosterone levels to the normal range in patients with cirrhosis; and a two year placebo controlled randomised trial of the effects of intervention (a bisphosphonate proven to have antifracture efficacy in postmenopausal women or HRT) on BMD in patients with cirrhosis. 12.0 APPENDIX Contributors The Consensus Workshop Group Hepatology: D Jones, Freeman Hospital, Newcastle upon Tyne; J Collier, John Radcliffe Hospital, Oxford; R Chapman, John Radcliffe Hospital, Oxford; A MacGilchrist, Royal Infirmary, Edinburgh; A Burroughs, Royal Free Hospital, London; G Alexander, Addenbrookes Hospital, Cambridge; M Ninkovic, Addenbrookes Hospital, Cambridge; E Elias, Queen Elizabeth Hospital, Birmingham; A Dhawan, Kings College Hospital, London; M Davies, St James Hospital, Leeds; P Mills, Glasgow; D Gleeson, Sheffield; N Sheron, Southampton. |
| doi_str_mv | 10.1136/gut.50.suppl_1.i1 |
| format | Article |
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[...]irrespective of other factors, the incidence of osteoporosis increases in the elderly as age related bone loss is a normal phenomenon. Current research requirements include: a prospective study of the prevalence of fractures in patients with chronic liver disease; a study of the prevalence of osteoporosis in patients with all stages of PBC compared with sex and age matched controls; a prospective study of the prevalence of hypogonadism in males with cirrhosis with and without osteoporosis; assessment of the safety of restoring testosterone levels to the normal range in patients with cirrhosis; and a two year placebo controlled randomised trial of the effects of intervention (a bisphosphonate proven to have antifracture efficacy in postmenopausal women or HRT) on BMD in patients with cirrhosis. 12.0 APPENDIX Contributors The Consensus Workshop Group Hepatology: D Jones, Freeman Hospital, Newcastle upon Tyne; J Collier, John Radcliffe Hospital, Oxford; R Chapman, John Radcliffe Hospital, Oxford; A MacGilchrist, Royal Infirmary, Edinburgh; A Burroughs, Royal Free Hospital, London; G Alexander, Addenbrookes Hospital, Cambridge; M Ninkovic, Addenbrookes Hospital, Cambridge; E Elias, Queen Elizabeth Hospital, Birmingham; A Dhawan, Kings College Hospital, London; M Davies, St James Hospital, Leeds; P Mills, Glasgow; D Gleeson, Sheffield; N Sheron, Southampton.</description><identifier>ISSN: 0017-5749</identifier><identifier>EISSN: 1468-3288</identifier><identifier>EISSN: 1458-3288</identifier><identifier>DOI: 10.1136/gut.50.suppl_1.i1</identifier><identifier>PMID: 11788576</identifier><identifier>CODEN: GUTTAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Age ; Alcohol ; Biological and medical sciences ; Biomarkers ; BMD ; Body mass index ; Bone density ; bone mineral density ; Calcitonin - therapeutic use ; Calcium - administration & dosage ; Chronic Disease ; Dietary Supplements ; Diphosphonates - therapeutic use ; Diseases of the osteoarticular system ; Drug Combinations ; dual energy x ray absorptiometry ; DXA ; follicle stimulating hormone ; Fractures ; Fractures, Bone - etiology ; FSH ; guidelines ; Hepatology ; hormone replacement therapy ; Hormone Replacement Therapy - methods ; Hospitals ; HRT ; Humans ; Liver cirrhosis ; liver disease ; Liver diseases ; Liver Diseases - complications ; luteinising hormone ; Medical sciences ; Mens health ; Osteoporosis ; Osteoporosis - complications ; Osteoporosis - therapy ; Osteoporosis. Osteomalacia. Paget disease ; PBC ; Phosphatase ; primary biliary cirrhosis ; primary sclerosing cholangitis ; PSC ; Risk Factors ; sex hormone binding globulin ; SHBG ; Steroids - therapeutic use ; Supplement ; Testosterone ; Vitamin D - administration & dosage ; Womens health</subject><ispartof>Gut, 2002-02, Vol.50 (suppl 1), p.i1-9</ispartof><rights>Copyright 2002 by Gut</rights><rights>2002 INIST-CNRS</rights><rights>Copyright: 2002 Copyright 2002 by Gut</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b530t-9e731f11e722b7332b293123c805474df12a9b2d1b6813564b8ca140fd420ccd3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867644/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867644/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13426415$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11788576$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Collier, J D</creatorcontrib><creatorcontrib>Ninkovic, M</creatorcontrib><creatorcontrib>Compston, J E</creatorcontrib><title>Guidelines on the management of osteoporosis associated with chronic liver disease</title><title>Gut</title><addtitle>Gut</addtitle><description>Peak bone mass is determined by genetic factors, hormonal status, diet, and exercise, and men have a higher peak bone mass than women. [...]irrespective of other factors, the incidence of osteoporosis increases in the elderly as age related bone loss is a normal phenomenon. Current research requirements include: a prospective study of the prevalence of fractures in patients with chronic liver disease; a study of the prevalence of osteoporosis in patients with all stages of PBC compared with sex and age matched controls; a prospective study of the prevalence of hypogonadism in males with cirrhosis with and without osteoporosis; assessment of the safety of restoring testosterone levels to the normal range in patients with cirrhosis; and a two year placebo controlled randomised trial of the effects of intervention (a bisphosphonate proven to have antifracture efficacy in postmenopausal women or HRT) on BMD in patients with cirrhosis. 12.0 APPENDIX Contributors The Consensus Workshop Group Hepatology: D Jones, Freeman Hospital, Newcastle upon Tyne; J Collier, John Radcliffe Hospital, Oxford; R Chapman, John Radcliffe Hospital, Oxford; A MacGilchrist, Royal Infirmary, Edinburgh; A Burroughs, Royal Free Hospital, London; G Alexander, Addenbrookes Hospital, Cambridge; M Ninkovic, Addenbrookes Hospital, Cambridge; E Elias, Queen Elizabeth Hospital, Birmingham; A Dhawan, Kings College Hospital, London; M Davies, St James Hospital, Leeds; P Mills, Glasgow; D Gleeson, Sheffield; N Sheron, Southampton.</description><subject>Age</subject><subject>Alcohol</subject><subject>Biological and medical sciences</subject><subject>Biomarkers</subject><subject>BMD</subject><subject>Body mass index</subject><subject>Bone density</subject><subject>bone mineral density</subject><subject>Calcitonin - therapeutic use</subject><subject>Calcium - administration & dosage</subject><subject>Chronic Disease</subject><subject>Dietary Supplements</subject><subject>Diphosphonates - therapeutic use</subject><subject>Diseases of the osteoarticular system</subject><subject>Drug Combinations</subject><subject>dual energy x ray absorptiometry</subject><subject>DXA</subject><subject>follicle stimulating hormone</subject><subject>Fractures</subject><subject>Fractures, Bone - etiology</subject><subject>FSH</subject><subject>guidelines</subject><subject>Hepatology</subject><subject>hormone replacement therapy</subject><subject>Hormone Replacement Therapy - methods</subject><subject>Hospitals</subject><subject>HRT</subject><subject>Humans</subject><subject>Liver cirrhosis</subject><subject>liver disease</subject><subject>Liver diseases</subject><subject>Liver Diseases - complications</subject><subject>luteinising hormone</subject><subject>Medical sciences</subject><subject>Mens health</subject><subject>Osteoporosis</subject><subject>Osteoporosis - complications</subject><subject>Osteoporosis - therapy</subject><subject>Osteoporosis. Osteomalacia. Paget disease</subject><subject>PBC</subject><subject>Phosphatase</subject><subject>primary biliary cirrhosis</subject><subject>primary sclerosing cholangitis</subject><subject>PSC</subject><subject>Risk Factors</subject><subject>sex hormone binding globulin</subject><subject>SHBG</subject><subject>Steroids - therapeutic use</subject><subject>Supplement</subject><subject>Testosterone</subject><subject>Vitamin D - administration & dosage</subject><subject>Womens health</subject><issn>0017-5749</issn><issn>1468-3288</issn><issn>1458-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkV-L1DAUxYMo7jj6AXyRgOiTHXOTtEleFmTQVVwUB_88hjRNZzK2TU3aVb-9kSm76pNPCdzfPZx7DkIPgWwAWPV8P0-bkmzSPI6dho2HW2gFvJIFo1LeRitCQBSl4OoM3UvpSAiRUsFddAYgpCxFtUK7i9k3rvODSzgMeDo43JvB7F3vhgmHFoc0uTCGGJJP2KQUrDeTa_B3Px2wPcQweIs7f-UibnxyJrn76E5ruuQeLO8afXr18uP2dXH5_uLN9sVlUZeMTIVygkEL4ASltWCM1lQxoMxKUnLBmxaoUTVtoK4ksLLitbQGOGkbTom1DVuj85PuONe9a2w2HE2nx-h7E3_qYLz-ezL4g96HKw2yEhXnWeDpIhDDt9mlSfc-Wdd1ZnBhTlrkjJUgIoOP_wGPYY5DPk6DEErxHCfJFJwom8NK0bXXVoDo333p3JcuiV760h7yzqM_b7jZWArKwJMFMMmaro1msD7dcIzTikOZueLE-dzXj-u5iV91JZgo9bvPW_2FfVBq93aXP2v07MTX_fE_fP4CiynAgw</recordid><startdate>20020201</startdate><enddate>20020201</enddate><creator>Collier, J D</creator><creator>Ninkovic, M</creator><creator>Compston, J E</creator><general>BMJ Publishing Group Ltd and British Society of Gastroenterology</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20020201</creationdate><title>Guidelines on the management of osteoporosis associated with chronic liver disease</title><author>Collier, J D ; Ninkovic, M ; Compston, J E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b530t-9e731f11e722b7332b293123c805474df12a9b2d1b6813564b8ca140fd420ccd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Age</topic><topic>Alcohol</topic><topic>Biological and medical sciences</topic><topic>Biomarkers</topic><topic>BMD</topic><topic>Body mass index</topic><topic>Bone density</topic><topic>bone mineral density</topic><topic>Calcitonin - therapeutic use</topic><topic>Calcium - administration & dosage</topic><topic>Chronic Disease</topic><topic>Dietary Supplements</topic><topic>Diphosphonates - therapeutic use</topic><topic>Diseases of the osteoarticular system</topic><topic>Drug Combinations</topic><topic>dual energy x ray absorptiometry</topic><topic>DXA</topic><topic>follicle stimulating hormone</topic><topic>Fractures</topic><topic>Fractures, Bone - etiology</topic><topic>FSH</topic><topic>guidelines</topic><topic>Hepatology</topic><topic>hormone replacement therapy</topic><topic>Hormone Replacement Therapy - methods</topic><topic>Hospitals</topic><topic>HRT</topic><topic>Humans</topic><topic>Liver cirrhosis</topic><topic>liver disease</topic><topic>Liver diseases</topic><topic>Liver Diseases - complications</topic><topic>luteinising hormone</topic><topic>Medical sciences</topic><topic>Mens health</topic><topic>Osteoporosis</topic><topic>Osteoporosis - complications</topic><topic>Osteoporosis - therapy</topic><topic>Osteoporosis. Osteomalacia. Paget disease</topic><topic>PBC</topic><topic>Phosphatase</topic><topic>primary biliary cirrhosis</topic><topic>primary sclerosing cholangitis</topic><topic>PSC</topic><topic>Risk Factors</topic><topic>sex hormone binding globulin</topic><topic>SHBG</topic><topic>Steroids - therapeutic use</topic><topic>Supplement</topic><topic>Testosterone</topic><topic>Vitamin D - administration & dosage</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Collier, J D</creatorcontrib><creatorcontrib>Ninkovic, M</creatorcontrib><creatorcontrib>Compston, J E</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Gut</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Collier, J D</au><au>Ninkovic, M</au><au>Compston, J E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Guidelines on the management of osteoporosis associated with chronic liver disease</atitle><jtitle>Gut</jtitle><addtitle>Gut</addtitle><date>2002-02-01</date><risdate>2002</risdate><volume>50</volume><issue>suppl 1</issue><spage>i1</spage><epage>9</epage><pages>i1-9</pages><issn>0017-5749</issn><eissn>1468-3288</eissn><eissn>1458-3288</eissn><coden>GUTTAK</coden><abstract>Peak bone mass is determined by genetic factors, hormonal status, diet, and exercise, and men have a higher peak bone mass than women. [...]irrespective of other factors, the incidence of osteoporosis increases in the elderly as age related bone loss is a normal phenomenon. Current research requirements include: a prospective study of the prevalence of fractures in patients with chronic liver disease; a study of the prevalence of osteoporosis in patients with all stages of PBC compared with sex and age matched controls; a prospective study of the prevalence of hypogonadism in males with cirrhosis with and without osteoporosis; assessment of the safety of restoring testosterone levels to the normal range in patients with cirrhosis; and a two year placebo controlled randomised trial of the effects of intervention (a bisphosphonate proven to have antifracture efficacy in postmenopausal women or HRT) on BMD in patients with cirrhosis. 12.0 APPENDIX Contributors The Consensus Workshop Group Hepatology: D Jones, Freeman Hospital, Newcastle upon Tyne; J Collier, John Radcliffe Hospital, Oxford; R Chapman, John Radcliffe Hospital, Oxford; A MacGilchrist, Royal Infirmary, Edinburgh; A Burroughs, Royal Free Hospital, London; G Alexander, Addenbrookes Hospital, Cambridge; M Ninkovic, Addenbrookes Hospital, Cambridge; E Elias, Queen Elizabeth Hospital, Birmingham; A Dhawan, Kings College Hospital, London; M Davies, St James Hospital, Leeds; P Mills, Glasgow; D Gleeson, Sheffield; N Sheron, Southampton.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><pmid>11788576</pmid><doi>10.1136/gut.50.suppl_1.i1</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Age Alcohol Biological and medical sciences Biomarkers BMD Body mass index Bone density bone mineral density Calcitonin - therapeutic use Calcium - administration & dosage Chronic Disease Dietary Supplements Diphosphonates - therapeutic use Diseases of the osteoarticular system Drug Combinations dual energy x ray absorptiometry DXA follicle stimulating hormone Fractures Fractures, Bone - etiology FSH guidelines Hepatology hormone replacement therapy Hormone Replacement Therapy - methods Hospitals HRT Humans Liver cirrhosis liver disease Liver diseases Liver Diseases - complications luteinising hormone Medical sciences Mens health Osteoporosis Osteoporosis - complications Osteoporosis - therapy Osteoporosis. Osteomalacia. Paget disease PBC Phosphatase primary biliary cirrhosis primary sclerosing cholangitis PSC Risk Factors sex hormone binding globulin SHBG Steroids - therapeutic use Supplement Testosterone Vitamin D - administration & dosage Womens health |
| title | Guidelines on the management of osteoporosis associated with chronic liver disease |
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