Molecular Genetic Aspects of Oligodendrogliomas Including Analysis by Comparative Genomic Hybridization

Oligodendroglial neoplasms are a subgroup of gliomas with distinctive morphological characteristics. In the present study we have evaluated a series of these tumors to define their molecular profiles and to determine whether there is a relationship between molecular genetic parameters and histologic...

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Veröffentlicht in:	The American journal of pathology 1999-08, Vol.155 (2), p.375-386
Hauptverfasser:	Bigner, Sandra H., Matthews, Mark R., Rasheed, B.K.A., Wiltshire, Rodney N., Friedman, Henry S., Friedman, Allan H., Stenzel, Timothy T., Dawes, Donald M., McLendon, Roger E., Bigner, Darell D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Astrocytoma - genetics Biological and medical sciences Brain Neoplasms - genetics Brain Neoplasms - pathology Child Chromosome Deletion Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 19 Chromosomes, Human, Pair 4 Female Genes, p16 - genetics Genes, p53 - genetics Glioblastoma - genetics Humans Loss of Heterozygosity Male Medical sciences Middle Aged Neoplasm Recurrence, Local - genetics Neurology Nucleic Acid Hybridization - methods Oligodendroglioma - genetics Oligodendroglioma - pathology Phosphoric Monoester Hydrolases - genetics Polymerase Chain Reaction Polymorphism, Single-Stranded Conformational PTEN Phosphohydrolase Regular Tumor Suppressor Proteins Tumors of the nervous system. Phacomatoses Y Chromosome
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