Differentiation of embryonic stem cells is induced by GATA factors

Extraembryonic endoderm (ExE) is differentiated from the inner cell mass of the late blastocyst-stage embryo to form visceral and parietal endoderm, both of which have an important role in early embryogenesis. The essential roles of Gata-6 and Gata-4 on differentiation of visceral endoderm have been...

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Veröffentlicht in:	Genes & development 2002-04, Vol.16 (7), p.784-789
Hauptverfasser:	Fujikura, Junji, Yamato, Eiji, Yonemura, Shigenobu, Hosoda, Kiminori, Masui, Shinji, Nakao, Kazuwa, Miyazaki Ji, Jun-ichi, Niwa, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Northern Blotting, Western Cell Differentiation Cell Nucleus - metabolism Cell Nucleus - ultrastructure DNA, Complementary - metabolism DNA-Binding Proteins - metabolism Endoderm - metabolism GATA protein GATA4 Transcription Factor GATA6 Transcription Factor Humans Mice Microscopy, Electron Models, Biological Plasmids - metabolism Rats Research Communication Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Time Factors Transcription Factors - metabolism Transcription, Genetic Transfection
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