Autoimmunity in chronic active Helicobacter hepatitis of mice. Serum antibodies and expression of heat shock protein 70 in liver

Male A/JCr mice with naturally occurring Helicobacter hepaticus infection develop a progressive chronic active hepatitis and liver tumors, despite the presence of serum antibodies to Helicobacter proteins. A rabbit antiserum prepared against the bacterial proteins immunoreacted with hepatocytes pres...

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Veröffentlicht in:	The American journal of pathology 1996-02, Vol.148 (2), p.509-517
Hauptverfasser:	Ward, JM, Benveniste, RE, Fox, CH, Battles, JK, Gonda, MA, Tully, JG
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma, Liver Cell - microbiology Animal bacterial diseases Animals Antibodies, Bacterial - blood Autoantibodies - blood Bacterial diseases Biological and medical sciences CD3 Complex - analysis Gallbladder - microbiology Gallbladder - pathology Helicobacter - immunology Helicobacter - isolation & purification Helicobacter Infections - immunology Helicobacter Infections - microbiology Helicobacter Infections - pathology Hepatitis, Chronic - immunology Hepatitis, Chronic - microbiology Hepatitis, Chronic - pathology HSP70 Heat-Shock Proteins - biosynthesis HSP70 Heat-Shock Proteins - immunology Immunoblotting In Situ Hybridization Infectious diseases Liver - immunology Liver - metabolism Liver - pathology Liver Neoplasms - microbiology Male Medical sciences Mice Mice, Inbred A Rabbits RNA, Ribosomal, 16S - analysis T-Lymphocytes - immunology
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