Centrilobular necrosis in autoimmune hepatitis: a histological feature associated with acute clinical presentation

Aims: The characteristic histological feature of autoimmune hepatitis (AIH) is interface hepatitis with predominant portal lymphoplasmacytic necroinflammatory infiltration. Centrilobular necrosis (CN), reminiscent of toxic or circulatory liver injury, has been reported in AIH. The aim of this study...

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Veröffentlicht in:	Journal of clinical pathology 2006-03, Vol.59 (3), p.246-249
Hauptverfasser:	Hofer, H, Oesterreicher, C, Wrba, F, Ferenci, P, Penner, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult AIH AMA ANA anti-nuclear antibodies antimitochondrial antibodies autoimmune hepatitis Bile Bile Ducts - pathology Biological and medical sciences Case-Control Studies centrilobular necrosis Chi-Square Distribution Female Fibrosis Gangrene Gastroenterology. Liver. Pancreas. Abdomen HAI hepatic activity index Hepatitis Hepatitis, Autoimmune - pathology Hepatocytes - pathology histopathology Humans IAIHG Immunoglobulins Inflammation International Autoimmune Hepatitis Study Group Investigative techniques, diagnostic techniques (general aspects) Laboratories Liver - pathology Liver cirrhosis Liver diseases liver kidney microsomes Liver. Biliary tract. Portal circulation. Exocrine pancreas LKM Male Medical sciences Middle Aged Necrosis OLT Original orthotopic liver transplantation Other diseases. Semiology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques recent onset AIH Rodents SMA Smooth muscle smooth muscle antibodies Statistics, Nonparametric Studies Transplants & implants zone 3 necrosis
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