The tryptase positive compact round cell infiltrate of the bone marrow (TROCI-BM): a novel histopathological finding requiring the application of lineage specific markers

Aims: Compact tryptase-positive round cell infiltrates of the bone marrow (TROCI-BM) are very rare histopathological findings and may pose challenging problems with regard to the cell type involved (either mast cells or basophilic granulocytes) and the exact diagnosis. Methods: A selected panel of i...

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Veröffentlicht in:	Journal of clinical pathology 2006-03, Vol.59 (3), p.298-302
Hauptverfasser:	Horny, H-P, Sotlar, K, Stellmacher, F, Krokowski, M, Agis, H, Schwartz, L B, Valent, P
Format:	Artikel
Sprache:	eng
Schlagworte:	acute myeloid leukaemia Adult Aged Aged, 80 and over AML basophilic leukaemia Basophils - chemistry Biological and medical sciences Biomarkers - analysis Bone Marrow Cells - enzymology Cell Lineage chronic myeloid leukaemia chronic myeloid leukaemia with excess of basophils CML CMLba Female Humans Immunohistochemistry - methods Immunophenotyping indolent systemic mastocytosis Investigative techniques, diagnostic techniques (general aspects) ISM Leukemia, Mast-Cell - diagnosis Male mast cell leukaemia mast cell leukaemias Mast Cells - chemistry Mastocytosis - diagnosis MCL Medical sciences Middle Aged MML myelomastocytic leukaemia Original Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Point Mutation Proto-Oncogene Proteins c-kit - genetics Receptors, Interleukin-2 - analysis Retrospective Studies Serine Endopeptidases - analysis systemic mastocytosis TROCI-BM tryptase tryptase-positive compact round cell infiltrate of the bone marrow Tryptases
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