Role of Epstein-Barr virus DNA measurement in plasma in the clinical management of nasopharyngeal carcinoma in a low risk area

Objective: To evaluate the role of quantitative measurement of Epstein-Barr virus (EBV) DNA in the clinical management of nasopharyngeal carcinoma (NPC) in a low tumour risk area (western Europe). Methods: 22 consecutive Dutch NPC patients (11 europid) were studied. EBV DNA load in pretreatment and...

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Veröffentlicht in:	Journal of clinical pathology 2006-05, Vol.59 (5), p.537-541
Hauptverfasser:	Kalpoe, J S, Douwes Dekker, P B, van Krieken, J H J M, Baatenburg de Jong, R J, Kroes, A C M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Biomarkers, Tumor - analysis Biomarkers, Tumor - blood Carcinoma - therapy Carcinoma - virology DNA, Viral - analysis DNA, Viral - blood EBER EBV Epstein-Barr virus Epstein-Barr virus DNA Epstein-Barr virus encoded RNA Female Follow-Up Studies Herpesvirus 4, Human - genetics Humans in situ hybridisation International Union Against Cancer Investigative techniques, diagnostic techniques (general aspects) ISH Male Medical sciences Middle Aged nasopharyngeal carcinoma Nasopharyngeal Neoplasms - therapy Nasopharyngeal Neoplasms - virology Neoplasm Recurrence, Local - virology NPC Original Otorhinolaryngology. Stomatology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Polymerase Chain Reaction - methods quantitative PCR Risk Sensitivity and Specificity Tumors UICC Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Viral Load
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