Respiratory syncytial virus induces interleukin-10 by human alveolar macrophages. Suppression of early cytokine production and implications for incomplete immunity

Respiratory syncytial virus (RSV) causes repeated infections thought to be due to an ineffective immune response. We examined the hypothesis that incomplete immunity may result, in part, from RSV-infected alveolar macrophage production of IL-10 which can interfere with the production of immunoregula...

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Veröffentlicht in:	The Journal of clinical investigation 1995-11, Vol.96 (5), p.2445-2453
Hauptverfasser:	Panuska, J R, Merolla, R, Rebert, N A, Hoffmann, S P, Tsivitse, P, Cirino, N M, Silverman, R H, Rankin, J A
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cells, Cultured Humans Interleukin-1 - biosynthesis Interleukin-10 - biosynthesis Lipopolysaccharides - pharmacology Macrophages, Alveolar - immunology Macrophages, Alveolar - virology Molecular Sequence Data Polymerase Chain Reaction Respiratory Syncytial Virus Infections - immunology Respiratory Syncytial Viruses Tumor Necrosis Factor-alpha - biosynthesis
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