Patterns of allelic loss (LOH) in vulvar squamous carcinomas and adjacent noninvasive epithelia

The pathogenesis of carcinoma of the vulva is diverse and includes both human papilloma virus (HPV)-positive and HPV-negative pathways. The objective of this study was to correlate the morphology with patterns of loss of heterozygosity (LOH) within four vulvar carcinomas and in adjacent vulvar epith...

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Veröffentlicht in:	The American journal of pathology 1998-05, Vol.152 (5), p.1313-1318
Hauptverfasser:	Lin, MC, Mutter, GL, Trivijisilp, P, Boynton, KA, Sun, D, Crum, CP
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma in Situ - genetics Carcinoma in Situ - pathology Carcinoma in Situ - virology Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - virology DNA, Neoplasm - genetics DNA, Viral Epithelium - pathology Epithelium - virology Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Hyperplasia Loss of Heterozygosity Medical sciences Mucous Membrane - pathology Mucous Membrane - virology Papillomaviridae - genetics Papillomaviridae - isolation & purification Polyomaviridae Retrospective Studies Tumor Virus Infections - complications Tumor Virus Infections - pathology Tumors Vulva - pathology Vulva - virology Vulvar Neoplasms - genetics Vulvar Neoplasms - pathology Vulvar Neoplasms - virology
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