Impairment of selectin-mediated leukocyte adhesion to venular endothelium in spontaneously hypertensive rats

The present study was designed to elucidate whether molecular mechanisms for leukocyte adhesion to microvascular endothelium may differ between spontaneously hypertensive rats and Wistar Kyoto rats. Leukocyte rolling and adhesion were investigated while monitoring venular wall shear rates in the mes...

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Veröffentlicht in:	The Journal of clinical investigation 1995-10, Vol.96 (4), p.2009-2016
Hauptverfasser:	Suematsu, M, Suzuki, H, Tamatani, T, Iigou, Y, DeLano, F A, Miyasaka, M, Forrest, M J, Kannagi, R, Zweifach, B W, Ishimura, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion CHO Cells Cricetinae Endothelium, Vascular - cytology Endothelium, Vascular - physiology Histamine - pharmacology Hypertension - blood Leukocytes - physiology Male Neutrophils - physiology P-Selectin - analysis P-Selectin - physiology Peroxides - pharmacology Rats Rats, Inbred SHR Rats, Inbred WKY tert-Butylhydroperoxide
Online-Zugang:	Volltext
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