Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis

Clusterin, a widely distributed glycoprotein, is detected in most tissues and in numerous physiological fluids. In the kidney, this protein is constitutively expressed in tubular epithelial cells, and its expression is enhanced following tubular injuries. In addition, clusterin has been detected in...

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Veröffentlicht in:	The American journal of pathology 1998-04, Vol.152 (4), p.953-962
Hauptverfasser:	Moll, S, Menoud, PA, French, L, Sappino, AP, Pastore, Y, Schifferli, JA, Izui, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Clusterin Complement Inactivator Proteins - metabolism Female Gene Expression Regulation Glycoproteins - metabolism Heymann Nephritis Antigenic Complex Immunoglobulin G - adverse effects In Situ Hybridization Kidney Diseases - chemically induced Kidney Diseases - metabolism Kidney Diseases - pathology Kidney Glomerulus - immunology Kidney Glomerulus - metabolism Kidney Glomerulus - pathology Kidney Tubular Necrosis, Acute - chemically induced Kidney Tubular Necrosis, Acute - metabolism Kidney Tubular Necrosis, Acute - pathology Kidney Tubules - metabolism Kidney Tubules - pathology Kidneys Lipopolysaccharides - adverse effects Lupus Vulgaris - metabolism Lupus Vulgaris - pathology Male Medical sciences Membrane Glycoproteins - metabolism Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred Strains Molecular Chaperones Nephritis - chemically induced Nephritis - metabolism Nephritis - pathology Nephrology. Urinary tract diseases Nerve Tissue Proteins - metabolism RNA, Messenger - analysis Urinary system involvement in other diseases. Miscellaneous
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