Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape

The discoid form of blood platelets is important to their function in hemostasis. Recent studies have suggested that the spectrin-rich surface membrane cytoskeleton and the cytoplasmic, actin-rich cytoskeleton are responsible for discoid shape, shape change, and recovery after activation or chilling...

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Veröffentlicht in:	The American journal of pathology 1998-02, Vol.152 (2), p.597-609
Hauptverfasser:	White, JG, Rao, GH
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - antagonists & inhibitors Actins - physiology Biological and medical sciences Blood coagulation. Blood cells Blood Platelets - cytology Blood Platelets - physiology Blood Platelets - ultrastructure Cell Membrane - physiology Colchicine - pharmacology Cold Temperature Cytochalasin B - pharmacology Cytoskeleton - physiology Fundamental and applied biological sciences. Psychology Hot Temperature Humans Microtubules - drug effects Microtubules - physiology Molecular and cellular biology Nocodazole - pharmacology Paclitaxel - pharmacology Platelet Reference Values Temperature Vincristine - pharmacology
Online-Zugang:	Volltext
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