Autoimmune hepatitis triggered by hepatitis A
AST (or ALT) ratio >3 -2 2.0 +3 1.5-2.0 +2 1.0-1.5 +1 1:80 +3 1:80 +2 1:40 +1 15 Probable diagnosis 10-15 Post-treatment score Definite diagnosis >17 Probable diagnosis 12-17 ALP, alkaline phosphatase; ALT, alanine aminotransferase antinuclear; AMA, antimitochondrial antibodies; ANA, antinucle...
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description | AST (or ALT) ratio >3 -2 2.0 +3 1.5-2.0 +2 1.0-1.5 +1 1:80 +3 1:80 +2 1:40 +1 15 Probable diagnosis 10-15 Post-treatment score Definite diagnosis >17 Probable diagnosis 12-17 ALP, alkaline phosphatase; ALT, alanine aminotransferase antinuclear; AMA, antimitochondrial antibodies; ANA, antinuclear antibodies; anti-SLA/LP, antibodies to soluble liver antigen/liver panareas; anti-LCq, antibodies to liver cytosol type 1; AST, aspartate aminotransferase; LKM, antiliver, kidney and pancreas antibodies; pANCA, perinuclear antineutrophil cytoplasmic antibodies. [...]diligent follow up of patients with acute hepatitis A needs to be carried out. |
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[...]diligent follow up of patients with acute hepatitis A needs to be carried out.</description><identifier>ISSN: 0017-5749</identifier><identifier>EISSN: 1468-3288</identifier><identifier>DOI: 10.1136/gut.2006.111864</identifier><identifier>PMID: 17303607</identifier><identifier>CODEN: GUTTAK</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Acute Disease ; Female ; Hepatitis ; Hepatitis A - complications ; Hepatitis, Autoimmune - etiology ; Histology ; Humans ; Immunoglobulins ; Infections ; Letter ; Liver ; Liver diseases ; Viral infections</subject><ispartof>Gut, 2007-02, Vol.56 (2), p.304-304</ispartof><rights>Copyright 2007 by Gut</rights><rights>Copyright: 2007 Copyright 2007 by Gut</rights><rights>Copyright © 2007 BMJ Publishing Group & British Society of Gastroenterology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b461t-860216871404f660ae4e07dd48222601d55287e25e14ad546a6244da768ff00a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://gut.bmj.com/content/56/2/304.1.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://gut.bmj.com/content/56/2/304.1.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,727,780,784,885,3195,23570,27923,27924,53790,53792,77471,77502</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17303607$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Singh, G</creatorcontrib><creatorcontrib>Palaniappan, S</creatorcontrib><creatorcontrib>Rotimi, O</creatorcontrib><creatorcontrib>Hamlin, P J</creatorcontrib><title>Autoimmune hepatitis triggered by hepatitis A</title><title>Gut</title><addtitle>Gut</addtitle><description>AST (or ALT) ratio >3 -2 <1.5 +2 [GAMMA]-globulin or IgG (x above upper limit of normal) >2.0 +3 1.5-2.0 +2 1.0-1.5 +1 <1.0 0 ANA, SMA or anti-LKM1 titres >1:80 +3 1:80 +2 1:40 +1 <1:40 0 AMA Positive -4 Viral markers of active infection Positive -3 Negative +3 Hepatotoxic drugs Yes -4 No +1 Alcohol <25 g/day +2 >60 g/day -2 Concurrent immune disease Any non-hepatic disease of an immune nature +2 Other autoantibodies Anti-SLA/LP, actin, LC1, pANCA +2 Histological features Interface hepatitis +3 Plasma cells +1 Rosettes +1 None of the above -5 Biliary changes -3 Atypical features -3 HLA DR3 or DR4 +1 Treatment response Remission alone +2 Remission with relapse +3 Pretreatment score Definite diagnosis >15 Probable diagnosis 10-15 Post-treatment score Definite diagnosis >17 Probable diagnosis 12-17 ALP, alkaline phosphatase; ALT, alanine aminotransferase antinuclear; AMA, antimitochondrial antibodies; ANA, antinuclear antibodies; anti-SLA/LP, antibodies to soluble liver antigen/liver panareas; anti-LCq, antibodies to liver cytosol type 1; AST, aspartate aminotransferase; LKM, antiliver, kidney and pancreas antibodies; pANCA, perinuclear antineutrophil cytoplasmic antibodies. [...]diligent follow up of patients with acute hepatitis A needs to be carried out.</description><subject>Acute Disease</subject><subject>Female</subject><subject>Hepatitis</subject><subject>Hepatitis A - complications</subject><subject>Hepatitis, Autoimmune - etiology</subject><subject>Histology</subject><subject>Humans</subject><subject>Immunoglobulins</subject><subject>Infections</subject><subject>Letter</subject><subject>Liver</subject><subject>Liver diseases</subject><subject>Viral infections</subject><issn>0017-5749</issn><issn>1468-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkLtPwzAQhy0EoqUws6FKbEhpz4_YzoJUlaeoYCmPzXIaJ01pkmI7iP73pEpVYGKyzvfd704fQqcYBhhTPsxqPyAAvKmw5GwPdTHjMqBEyn3UBcAiCAWLOujIuQUASBnhQ9TBggLlILooGNW-youiLk1_blba5z53fW_zLDPWJP14_et7dIwOUr105mT79tDzzfV0fBdMnm7vx6NJEDOOfSA5EMylwAxYyjlowwyIJGGSEMIBJ2FIpDAkNJjpJGRcc8JYogWXaQqgaQ9dtrmrOi5MMjOlt3qpVjYvtF2rSufqb6fM5yqrPhWWIReCNgHn2wBbfdTGebWoals2NyssRESppJFsqGFLzWzlnDXpbgMGtfGrGr9q41e1fpuJs9-H_fBboQ0QtEDuvPna9bV9V1xQEarHl7ES0ysxYQ-v6q3hL1o-Lhb_bv8GWS2RSQ</recordid><startdate>200702</startdate><enddate>200702</enddate><creator>Singh, G</creator><creator>Palaniappan, S</creator><creator>Rotimi, O</creator><creator>Hamlin, P J</creator><general>BMJ Publishing Group Ltd and British Society of Gastroenterology</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>5PM</scope></search><sort><creationdate>200702</creationdate><title>Autoimmune hepatitis triggered by hepatitis A</title><author>Singh, G ; Palaniappan, S ; Rotimi, O ; Hamlin, P J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b461t-860216871404f660ae4e07dd48222601d55287e25e14ad546a6244da768ff00a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Acute Disease</topic><topic>Female</topic><topic>Hepatitis</topic><topic>Hepatitis A - complications</topic><topic>Hepatitis, Autoimmune - etiology</topic><topic>Histology</topic><topic>Humans</topic><topic>Immunoglobulins</topic><topic>Infections</topic><topic>Letter</topic><topic>Liver</topic><topic>Liver diseases</topic><topic>Viral infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Singh, G</creatorcontrib><creatorcontrib>Palaniappan, S</creatorcontrib><creatorcontrib>Rotimi, O</creatorcontrib><creatorcontrib>Hamlin, P J</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Gut</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Singh, G</au><au>Palaniappan, S</au><au>Rotimi, O</au><au>Hamlin, P J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Autoimmune hepatitis triggered by hepatitis A</atitle><jtitle>Gut</jtitle><addtitle>Gut</addtitle><date>2007-02</date><risdate>2007</risdate><volume>56</volume><issue>2</issue><spage>304</spage><epage>304</epage><pages>304-304</pages><issn>0017-5749</issn><eissn>1468-3288</eissn><coden>GUTTAK</coden><abstract>AST (or ALT) ratio >3 -2 <1.5 +2 [GAMMA]-globulin or IgG (x above upper limit of normal) >2.0 +3 1.5-2.0 +2 1.0-1.5 +1 <1.0 0 ANA, SMA or anti-LKM1 titres >1:80 +3 1:80 +2 1:40 +1 <1:40 0 AMA Positive -4 Viral markers of active infection Positive -3 Negative +3 Hepatotoxic drugs Yes -4 No +1 Alcohol <25 g/day +2 >60 g/day -2 Concurrent immune disease Any non-hepatic disease of an immune nature +2 Other autoantibodies Anti-SLA/LP, actin, LC1, pANCA +2 Histological features Interface hepatitis +3 Plasma cells +1 Rosettes +1 None of the above -5 Biliary changes -3 Atypical features -3 HLA DR3 or DR4 +1 Treatment response Remission alone +2 Remission with relapse +3 Pretreatment score Definite diagnosis >15 Probable diagnosis 10-15 Post-treatment score Definite diagnosis >17 Probable diagnosis 12-17 ALP, alkaline phosphatase; ALT, alanine aminotransferase antinuclear; AMA, antimitochondrial antibodies; ANA, antinuclear antibodies; anti-SLA/LP, antibodies to soluble liver antigen/liver panareas; anti-LCq, antibodies to liver cytosol type 1; AST, aspartate aminotransferase; LKM, antiliver, kidney and pancreas antibodies; pANCA, perinuclear antineutrophil cytoplasmic antibodies. [...]diligent follow up of patients with acute hepatitis A needs to be carried out.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><pmid>17303607</pmid><doi>10.1136/gut.2006.111864</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acute Disease Female Hepatitis Hepatitis A - complications Hepatitis, Autoimmune - etiology Histology Humans Immunoglobulins Infections Letter Liver Liver diseases Viral infections |
title | Autoimmune hepatitis triggered by hepatitis A |
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