3‐Aminopropylphosphinic acid—a potent, selective GABAB receptor agonist in the guinea‐pig ileum and rat anococcygeus muscle

1 3‐Aminopropylphosphinic acid, a γ‐aminobutyric acid (GABA) analogue, was tested for activity on guinea‐pig isolated ileum and rat isolated anococcygeus muscle preparations. The effects of 3‐aminopropylphosphinic acid were compared with those of GABA and baclofen. 2 In the electrically stimulated i...

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Veröffentlicht in:	British journal of pharmacology 1989-08, Vol.97 (4), p.1292-1296
Hauptverfasser:	Hills, Judith M., Dingsdale, Rhona A., Parsons, Michael E., Dolle, Roland E., Howson, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baclofen - analogs & derivatives Baclofen - pharmacology Biological and medical sciences Guinea Pigs Ileum - drug effects In Vitro Techniques Male Medical sciences Miscellaneous Muscle Contraction - drug effects Muscle, Smooth - drug effects Muscles - drug effects Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Organophosphorus Compounds - antagonists & inhibitors Organophosphorus Compounds - pharmacology Parasympathetic Nervous System - drug effects Pharmacology. Drug treatments Rats Rats, Inbred Strains Receptors, GABA-A - drug effects
Online-Zugang:	Volltext
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