Purine receptors and guinea‐pig trachea: evidence for a direct action of ATP

1 Adenosine (3–300 μm) and ATP (1–300 μm) each induced concentration‐dependent relaxation of guinea‐pig isolated tracheal preparations that had been precontracted with methacholine. 2 Ectonucleotidase enzymes on the trachea dephosphorylated ATP to form adenosine which was then further metabolised to...

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Veröffentlicht in:	British journal of pharmacology 1988-11, Vol.95 (3), p.689-694
Hauptverfasser:	Welford, Laurence A., Anderson, Wayne H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - metabolism Adenosine - pharmacology Adenosine Triphosphate - pharmacology Adenylyl Imidodiphosphate - pharmacology Animals Biological and medical sciences Dipyridamole - pharmacology Female Fundamental and applied biological sciences. Psychology Guinea Pigs In Vitro Techniques Intermediate and energetic metabolism Male Metabolisms and neurohumoral controls Methacholine Compounds - pharmacology Receptors, Purinergic - drug effects Trachea - drug effects Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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