Inhibitory effect of 1,2,3,4‐tetrahydro‐9‐aminoacridine on the depolarization‐induced release of GABA from cerebral cortex

1,2,3,4‐Tetrahydro‐9‐aminoacridine (THA) has an inhibitory effect on the activity of acetylcholinesterase which has led to its use in the treatment of Alzheimer's disease. Other actions of THA include the inhibition of voltage‐dependent ion channels. In this paper we describe the effect of THA...

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Veröffentlicht in:	British journal of pharmacology 1988-08, Vol.94 (4), p.1017-1019
Hauptverfasser:	Belleroche, Jacqueline, Gardiner, Ian M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoacridines - pharmacology Animals Biological and medical sciences Cerebral Cortex - drug effects Cerebral Cortex - metabolism gamma-Aminobutyric Acid - metabolism In Vitro Techniques Medical sciences Miscellaneous Neuromuscular Depolarizing Agents - pharmacology Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Rats Tacrine - pharmacology
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