Cardiac and renovascular effects in the anaesthetized dog of BW A575C: a novel angiotensin converting enzyme inhibitor with β‐adrenoceptor blocking properties

1 In the anaesthetized open‐chest dog, BW A575C (N‐(1‐(S)‐carboxy‐5‐[4(3‐isopropylamino‐2‐(R,S)‐hydroxypropoxy)indole‐2‐carboxamido]pentyl)‐(R,S)‐alanyl‐(S)‐proline) causes a dose‐dependent inhibition of the isoprenaline response (increased cardiac rate). In this preparation BW A575C is approximatel...

Ausführliche Beschreibung