Bay K 8644‐induced changes in the ECG pattern of the rat and their inhibition by antianginal drugs

1 The effects of intracarotid administration of Bay K 8644 on the ECG pattern along with their reversal by antianginal drugs were investigated in anaesthetized rats. 2 Intracarotid injections of Bay K 8644 (0.5–50.0 μg kg−1) produced a dose‐related transient increase in systemic blood pressure. 3 Th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 1987-11, Vol.92 (3), p.603-608
Hauptverfasser:	Abraham, S., Amitai, G., Oz, N., Weissman, B.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester - antagonists & inhibitors 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester - pharmacology Animals Antianginal agents. Coronary vasodilator agents Atropine - pharmacology Biological and medical sciences Blood Pressure - drug effects Cardiovascular system Carotid Arteries Diltiazem - pharmacology Dose-Response Relationship, Drug Electrocardiography Injections, Intra-Arterial Isoquinolines - pharmacology Male Medical sciences Nifedipine - pharmacology Nitroglycerin - pharmacology Pharmacology. Drug treatments Phentolamine - pharmacology Rats Rats, Inbred Strains
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!