Unfolding of β-Sheet Proteins in SDS

β-Sheet proteins are particularly resistant to denaturation by sodium dodecyl sulfate (SDS). Here we compare unfolding of two β-sandwich proteins TNfn3 and TII27 in SDS. The two proteins show different surface electrostatic potential. Correspondingly, TII27 unfolds below the critical micelle concent...

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Veröffentlicht in:	Biophysical journal 2007-05, Vol.92 (10), p.3674-3685
Hauptverfasser:	Nielsen, Mette M., Andersen, Kell K., Westh, Peter, Otzen, Daniel E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Computer Simulation Models, Chemical Models, Molecular Protein Denaturation Protein Structure, Secondary Proteins Proteins - chemistry Proteins - ultrastructure Sodium Dodecyl Sulfate - chemistry
Online-Zugang:	Volltext
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