Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice

Flk-1+ endothelial progenitors contribute critically to the definitive onset of hematopoiesis during embryogenesis. Recent studies have suggested that adult sources of endothelial cells also possess hematopoietic activity. In this study, we sought to determine whether transplantation of primary vasc...

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Veröffentlicht in:	Blood 2007-03, Vol.109 (6), p.2365-2372
Hauptverfasser:	Chute, John P., Muramoto, Garrett G., Salter, Alice B., Meadows, Sarah K., Rickman, Dennis W., Chen, Benny, Himburg, Heather A., Chao, Nelson J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - cytology Brain - metabolism Cell Transplantation Cells, Cultured Cytokines - biosynthesis Endothelial Cells - cytology Endothelial Cells - metabolism Gene Expression Hematopoiesis Hematopoiesis - radiation effects Mice Stem Cells - cytology Survival Rate
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