The Role of Ultraviolet Irradiation and Heparin-Binding Epidermal Growth Factor-Like Growth Factor in the Pathogenesis of Pterygium

Ultraviolet (UV) light is one of the major factors implicated in the pathogenesis of pterygium. The mechanism by which UV light induces this disease remains elusive. The aim of this study was to evaluate the effects of UVB irradiation on the expression of growth factors in cultured pterygium epithel...

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Veröffentlicht in:	The American journal of pathology 2003-02, Vol.162 (2), p.567-574
Hauptverfasser:	Nolan, Timothy M., DiGirolamo, Nick, Sachdev, Nitin H., Hampartzoumian, Taline, Coroneo, Minas T., Wakefield, Denis
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Culture Techniques - methods Diseases of eyelid, conjunctiva and lacrimal tracts Enzyme-Linked Immunosorbent Assay Epidermal Growth Factor - radiation effects Epithelium, Corneal - pathology Heparin - radiation effects Heparin-binding EGF-like Growth Factor Humans Intercellular Signaling Peptides and Proteins Medical sciences Oligonucleotide Array Sequence Analysis Ophthalmology Pigment Epithelium of Eye - pathology Pterygium - genetics Pterygium - pathology Pterygium - physiopathology Regular Reverse Transcriptase Polymerase Chain Reaction Ultraviolet Rays
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