Expression Profiling of Synovial Sarcoma by cDNA Microarrays : Association of ERBB2, IGFBP2, and ELF3 with Epithelial Differentiation

Synovial sarcoma is an aggressive spindle cell sarcoma with two major histological subtypes, biphasic and monophasic, defined respectively by the presence or absence of areas of glandular epithelial differentiation. It is characterized by a specific chromosomal translocation, t(X;18)(p11.2;q11.2), w...

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Veröffentlicht in:	The American journal of pathology 2002-11, Vol.161 (5), p.1587-1595
Hauptverfasser:	Allander, Susanne V, Illei, Peter B, Chen, Yidong, Antonescu, Cristina R, Bittner, Mike, Ladanyi, Marc, Meltzer, Paul S
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Differentiation Dermatology DNA-Binding Proteins Epithelial Cells - cytology Gene Expression Profiling Humans Immunohistochemistry In Situ Hybridization, Fluorescence Insulin-Like Growth Factor Binding Protein 2 - biosynthesis Insulin-Like Growth Factor Binding Protein 2 - genetics Insulin-Like Growth Factor Binding Protein 2 - immunology Medical sciences Oligonucleotide Array Sequence Analysis Proto-Oncogene Proteins - biosynthesis Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - immunology Proto-Oncogene Proteins c-ets Receptor, ErbB-2 - biosynthesis Receptor, ErbB-2 - genetics Receptor, ErbB-2 - immunology Regular RNA, Neoplasm - analysis Sarcoma, Synovial - genetics Sarcoma, Synovial - metabolism Sarcoma, Synovial - pathology Transcription Factors - biosynthesis Transcription Factors - genetics Transcription Factors - immunology Tumor Cells, Cultured Tumors of the skin and soft tissue. Premalignant lesions
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