High-Throughput Copy Number Analysis of 17q23 in 3520 Tissue Specimens by Fluorescence in Situ Hybridization to Tissue Microarrays

The chromosomal region 17q23 has been shown to be commonly amplified in breast tumors, especially those with poor prognosis. In addition to breast cancer, studies by comparative genomic hybridization have implicated the involvement of 17q23 in other tumor types as well. Here we performed a large-sca...

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Veröffentlicht in:	The American journal of pathology 2002-07, Vol.161 (1), p.73-79
Hauptverfasser:	Andersen, Claus L., Monni, Outi, Wagner, Urs, Kononen, Juha, Bärlund, Maarit, Bucher, Christoph, Haas, Philippe, Nocito, Antonio, Bissig, Heidi, Sauter, Guido, Kallioniemi, Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Gene Amplification Gene Dosage General aspects Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Miscellaneous. Technology Neoplasm Metastasis - genetics Neoplasms - genetics Oligonucleotide Array Sequence Analysis Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Regular Tumors
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