Quantitative Gene Expression Analysis in Microdissected Archival Formalin-Fixed and Paraffin-Embedded Tumor Tissue

Formalin-fixed, paraffin-embedded tissue is the most widely available material for retrospective clinical studies. In combination with the potential of genomics, these tissues represent an invaluable resource for the elucidation of disease mechanisms and validation of differentially expressed genes...

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Veröffentlicht in:	The American journal of pathology 2001-02, Vol.158 (2), p.419-429
Hauptverfasser:	Specht, Katja, Richter, Thomas, Müller, Ulrike, Walch, Axel, Werner, Martin, Höfler, Heinz
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Dissection Fixatives Formaldehyde Frozen Sections Gene Expression Regulation, Neoplastic HT29 Cells Humans Investigative techniques, diagnostic techniques (general aspects) Laser Therapy Medical sciences Mice Mice, Nude Microsurgery Miscellaneous. Technology Neoplasms - genetics Neoplasms - pathology Neoplasms, Experimental - genetics Neoplasms, Experimental - pathology Paraffin Embedding Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Receptor, ErbB-2 - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Neoplasm - analysis RNA, Neoplasm - genetics RNA, Neoplasm - metabolism Technical Advance Time Factors Tissue Fixation Tumor Cells, Cultured
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