Ultrastructural evidence for co-localization of corticotropin-releasing factor receptor and μ-opioid receptor in the rat nucleus locus coeruleus

Previous studies have shown that corticotropin-releasing factor (CRF), an integral mediator of the stress response, and opioids regulate the activity of the locus-coeruleus-norepinephrine (LC-NE) system during stress in a reciprocal manner. Furthermore, repeated opiate exposure sensitizes noradrener...

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Veröffentlicht in:	Neuroscience letters 2007-02, Vol.413 (3), p.216-221
Hauptverfasser:	Reyes, Beverly A.S., Glaser, Julia D., Van Bockstaele, Elisabeth J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Corticotropin-releasing factor receptor 1 Electron microscopy Fluorescent Antibody Technique - methods Fundamental and applied biological sciences. Psychology Immunocytochemistry Locus Coeruleus - metabolism Locus Coeruleus - ultrastructure Male Microscopy, Immunoelectron - methods Models, Biological Rats Rats, Sprague-Dawley Receptors, Corticotropin-Releasing Hormone - metabolism Receptors, Opioid, mu - metabolism Tyrosine 3-Monooxygenase - metabolism Vertebrates: nervous system and sense organs μ-Opioid receptor
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