A Markov model approach to predicting regional tumor spread in the lymphatic system of the head and neck
Radiation planning for cancer therapy is becoming more and more dependent on the prediction of microscopic tumor spread to regional lymph nodes for its success. It is known that microscopic spread tends to follow established lymphatic drainage pathways in the head and neck based on the location of t...
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| Veröffentlicht in: | AMIA ... Annual Symposium proceedings 2006, Vol.2006, p.31-35 |
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| creator | Benson, Noah Whipple, Mark Kalet, Ira J |
| description | Radiation planning for cancer therapy is becoming more and more dependent on the prediction of microscopic tumor spread to regional lymph nodes for its success. It is known that microscopic spread tends to follow established lymphatic drainage pathways in the head and neck based on the location of the primary tumor. In this paper,we propose a novel model for the prediction of regional lymphatic involvement of head and neck squamous cell carcinoma based on primary tumor location and T-stage. The proposed model operates from first anatomical principles and basic stochastic techniques, and is validated against surgical data. |
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The proposed model operates from first anatomical principles and basic stochastic techniques, and is validated against surgical data.</description><subject>Carcinoma, Squamous Cell - secondary</subject><subject>Head and Neck Neoplasms - pathology</subject><subject>Humans</subject><subject>Lymph Nodes</subject><subject>Lymphatic Metastasis</subject><subject>Markov Chains</subject><subject>Models, Biological</subject><issn>1559-4076</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkEtLxDAUhYsgzjj6FyQrd4WmaV4bYRh8wYgbXZc0vZ3GaZOapAP991YdRVcX7jl8h3NOkiWmVKZFxtkiOQ_hLcsKTgU7SxaY50Tkki-Tdo2elN-7A-pdDR1Sw-Cd0i2KDg0eaqOjsTvkYWecVR2KY-88CrOkamQsii2gbuqHVkWjUZhChB655uvffnqUrZEFvb9IThvVBbg83lXyenf7snlIt8_3j5v1Nh0wlzEFBpopDUWNudK8wJQLwShh9VyDV0zSAoSUiuGcaJzphjayEHOdShCekYqskptv7jBWPdQabPSqKwdveuWn0ilT_lesacudO5RYEJnTfAZcHwHevY8QYtmboKHrlAU3hpLNw2HKstl49TfpN-JnXPIBXe92iA</recordid><startdate>2006</startdate><enddate>2006</enddate><creator>Benson, Noah</creator><creator>Whipple, Mark</creator><creator>Kalet, Ira J</creator><general>American Medical Informatics Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>2006</creationdate><title>A Markov model approach to predicting regional tumor spread in the lymphatic system of the head and neck</title><author>Benson, Noah ; Whipple, Mark ; Kalet, Ira J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p179t-e6ec6ace4d17ac74157886536d0767b6954e899a6123c10cf5f948723b83703b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Carcinoma, Squamous Cell - secondary</topic><topic>Head and Neck Neoplasms - pathology</topic><topic>Humans</topic><topic>Lymph Nodes</topic><topic>Lymphatic Metastasis</topic><topic>Markov Chains</topic><topic>Models, Biological</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Benson, Noah</creatorcontrib><creatorcontrib>Whipple, Mark</creatorcontrib><creatorcontrib>Kalet, Ira J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>AMIA ... 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| ispartof | AMIA ... Annual Symposium proceedings, 2006, Vol.2006, p.31-35 |
| issn | 1559-4076 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Carcinoma, Squamous Cell - secondary Head and Neck Neoplasms - pathology Humans Lymph Nodes Lymphatic Metastasis Markov Chains Models, Biological |
| title | A Markov model approach to predicting regional tumor spread in the lymphatic system of the head and neck |
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