Sex ratio and time to pregnancy: analysis of four large European population surveys

Objective To test whether the secondary sex ratio (proportion of male births) is associated with time to pregnancy, a marker of fertility. Design Analysis of four large population surveys.Setting Denmark and the United Kingdom.Participants 49 506 pregnancies.Main outcome measure Secondary sex ratio....

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Veröffentlicht in:BMJ 2007-03, Vol.334 (7592), p.524-526
Hauptverfasser: Joffe, Mike, Bennett, James, Best, Nicky, Jensen, Tina Kold
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container_title BMJ
container_volume 334
creator Joffe, Mike
Bennett, James
Best, Nicky
Jensen, Tina Kold
description Objective To test whether the secondary sex ratio (proportion of male births) is associated with time to pregnancy, a marker of fertility. Design Analysis of four large population surveys.Setting Denmark and the United Kingdom.Participants 49 506 pregnancies.Main outcome measure Secondary sex ratio. Results No association was found between the sex ratio and time to pregnancy and no discernible trend was found for sex ratio with time to pregnancy, either within individual datasets or in the pooled analysis. The odds ratios were 0.97 (95% confidence interval 0.90 to 1.04) for contraceptive failures, 1.01 (0.96 to 1.05) for time to pregnancy of 2-4 months, 1.02 (0.97 to 1.08) for 5-10 months, 0.98 (0.93 to 1.03) for 11 months or more, and 0.88 (0.74 to 1.06) for fertility treatment, with 0-1 months as the reference category.Conclusion No association was found between the secondary sex ratio and time to pregnancy.
doi_str_mv 10.1136/bmj.39097.508426.BE
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Design Analysis of four large population surveys.Setting Denmark and the United Kingdom.Participants 49 506 pregnancies.Main outcome measure Secondary sex ratio. Results No association was found between the sex ratio and time to pregnancy and no discernible trend was found for sex ratio with time to pregnancy, either within individual datasets or in the pooled analysis. The odds ratios were 0.97 (95% confidence interval 0.90 to 1.04) for contraceptive failures, 1.01 (0.96 to 1.05) for time to pregnancy of 2-4 months, 1.02 (0.97 to 1.08) for 5-10 months, 0.98 (0.93 to 1.03) for 11 months or more, and 0.88 (0.74 to 1.06) for fertility treatment, with 0-1 months as the reference category.Conclusion No association was found between the secondary sex ratio and time to pregnancy.</description><edition>International edition</edition><identifier>ISSN: 0959-8138</identifier><identifier>ISSN: 0959-8146</identifier><identifier>ISSN: 0959-535X</identifier><identifier>ISSN: 1756-1833</identifier><identifier>EISSN: 1468-5833</identifier><identifier>EISSN: 1756-1833</identifier><identifier>DOI: 10.1136/bmj.39097.508426.BE</identifier><identifier>PMID: 17277014</identifier><identifier>CODEN: BMJOAE</identifier><language>eng</language><publisher>London: British Medical Journal Publishing Group</publisher><subject>Biological and medical sciences ; Birth control ; Births ; Chemical hazards ; Childbirth &amp; labor ; Cohort studies ; Confidence interval ; Datasets ; Denmark ; Europe ; Female ; Fertility ; Fertility - physiology ; Gender ; General aspects ; Humans ; Male fertility ; Medical sciences ; Miscellaneous ; Population ; Population Surveillance ; Pregnancy ; Pregnancy - statistics &amp; numerical data ; Public health. 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Design Analysis of four large population surveys.Setting Denmark and the United Kingdom.Participants 49 506 pregnancies.Main outcome measure Secondary sex ratio. Results No association was found between the sex ratio and time to pregnancy and no discernible trend was found for sex ratio with time to pregnancy, either within individual datasets or in the pooled analysis. The odds ratios were 0.97 (95% confidence interval 0.90 to 1.04) for contraceptive failures, 1.01 (0.96 to 1.05) for time to pregnancy of 2-4 months, 1.02 (0.97 to 1.08) for 5-10 months, 0.98 (0.93 to 1.03) for 11 months or more, and 0.88 (0.74 to 1.06) for fertility treatment, with 0-1 months as the reference category.Conclusion No association was found between the secondary sex ratio and time to pregnancy.</description><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Births</subject><subject>Chemical hazards</subject><subject>Childbirth &amp; labor</subject><subject>Cohort studies</subject><subject>Confidence interval</subject><subject>Datasets</subject><subject>Denmark</subject><subject>Europe</subject><subject>Female</subject><subject>Fertility</subject><subject>Fertility - physiology</subject><subject>Gender</subject><subject>General aspects</subject><subject>Humans</subject><subject>Male fertility</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Population</subject><subject>Population Surveillance</subject><subject>Pregnancy</subject><subject>Pregnancy - statistics &amp; numerical data</subject><subject>Public health. 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Design Analysis of four large population surveys.Setting Denmark and the United Kingdom.Participants 49 506 pregnancies.Main outcome measure Secondary sex ratio. Results No association was found between the sex ratio and time to pregnancy and no discernible trend was found for sex ratio with time to pregnancy, either within individual datasets or in the pooled analysis. The odds ratios were 0.97 (95% confidence interval 0.90 to 1.04) for contraceptive failures, 1.01 (0.96 to 1.05) for time to pregnancy of 2-4 months, 1.02 (0.97 to 1.08) for 5-10 months, 0.98 (0.93 to 1.03) for 11 months or more, and 0.88 (0.74 to 1.06) for fertility treatment, with 0-1 months as the reference category.Conclusion No association was found between the secondary sex ratio and time to pregnancy.</abstract><cop>London</cop><pub>British Medical Journal Publishing Group</pub><pmid>17277014</pmid><doi>10.1136/bmj.39097.508426.BE</doi><tpages>3</tpages><edition>International edition</edition><oa>free_for_read</oa></addata></record>
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source Applied Social Sciences Index & Abstracts (ASSIA); Jstor Complete Legacy; MEDLINE; BMJ Journals - NESLi2; Alma/SFX Local Collection
subjects Biological and medical sciences
Birth control
Births
Chemical hazards
Childbirth & labor
Cohort studies
Confidence interval
Datasets
Denmark
Europe
Female
Fertility
Fertility - physiology
Gender
General aspects
Humans
Male fertility
Medical sciences
Miscellaneous
Population
Population Surveillance
Pregnancy
Pregnancy - statistics & numerical data
Public health. Hygiene
Public health. Hygiene-occupational medicine
Questionnaires
Ratios
Reproductive health
Semen analysis
Sex Ratio
Sex ratios
Time Factors
title Sex ratio and time to pregnancy: analysis of four large European population surveys
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