CD127 expression and regulation are altered in the memory CD8 T cells of HIV‐infected patients − reversal by highly active anti‐retroviral therapy (HAART)

Summary HIV infection activates abnormally the immune system and the chronic phase is accompanied by marked alterations in the CD8 compartment. The expression of CD127 (IL‐7R alpha chain) by memory CD8 T lymphocytes in HIV‐infected patients is analysed and reported. The memory CD8 T cell subset was...

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Veröffentlicht in:	Clinical and experimental immunology 2006-03, Vol.143 (3), p.398-403
Hauptverfasser:	Colle, J.‐H., Moreau, J.‐L., Fontanet, A., Lambotte, O., Joussemet, M., Delfraissy, J.‐F., Thèze, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiretroviral Therapy, Highly Active Biological and medical sciences CD127 CD8 T cells CD8-Positive T-Lymphocytes - immunology Cells, Cultured Fast Track Fundamental and applied biological sciences. Psychology Fundamental immunology HAART HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 Human immunodeficiency virus Humans IL‐7 Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunologic Memory Immunopathology Interleukin-7 - immunology Medical sciences memory subset receptor Receptors, Interleukin-7 - blood T-Lymphocyte Subsets - immunology viraemic patients Viral Load Viremia - immunology
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