Anisakis simplex allergy: a murine model of anaphylaxis induced by parasitic proteins displays a mixed Th1/Th2 pattern

Summary The study of the singular hypersensitivity reactions to Anisakis simplex (A.s) proteins, may help us to undestand many of the unknown immune interactions between helmiths infections and allergy. We have developed a murine model of allergy to A. simplex, that mimics human A. simplex allergy t...

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Veröffentlicht in:	Clinical and experimental immunology 2005-12, Vol.142 (3), p.433-440
Hauptverfasser:	Baeza, M. L., Conejero, L., Higaki, Y., Martín, E., Pérez, C., Infante, S., Rubio, M., Zubeldia, J. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology allergy to parasites anaphylaxis Anaphylaxis - immunology animal model Animal Studies Animals Anisakis - immunology Anisakis simplex Antigens, Helminth - immunology Biological and medical sciences Cytokines - analysis Disease Models, Animal Fundamental and applied biological sciences. Psychology Fundamental immunology Helminth Proteins - immunology helminths Histamine - blood Histamine Release - immunology Humans Immunoglobulin E - analysis Immunoglobulin G - analysis Immunopathology Male Medical sciences Mice Mice, Inbred C3H Spleen - cytology Spleen - immunology T-Lymphocytes, Helper-Inducer - immunology Th1 Cells - immunology Th2 Cells - immunology
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