Hepatic interleuklin 15 (IL‐15) expression: implications for local NK/NKT cell homeostasis and development

SUMMARY Interleukin 15 (IL‐15) is critical for the development of human and murine natural killer (NK) cells and hepatic‐derived NK T cells (NKT) in mice, and for the homeostatic maintenance of NK/NKT and CD8+ memory T cells. The lymphocyte repertoire of an adult human liver includes significant pop...

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Veröffentlicht in:	Clinical and experimental immunology 2004-10, Vol.138 (1), p.94-101
Hauptverfasser:	GOLDEN‐MASON, L., KELLY, A. M., DOHERTY, D. G., TRAYNOR, O., MCENTEE, G., KELLY, J., HEGARTY, J. E., O'FARRELLY, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antigens, CD - immunology Biological and medical sciences Clinical Studies Female Fundamental and applied biological sciences. Psychology Fundamental immunology Hematopoietic Stem Cells - immunology human Humans Immunohistochemistry - methods Immunopathology Interleukin-15 - analysis Interleukin-2 - analysis Killer Cells, Natural - immunology Liver - immunology lymphopoiesis Male Medical sciences Middle Aged NK cells normal liver Receptors, Interleukin-2 - analysis Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - analysis stem cells T-Lymphocytes - immunology
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