Antigens shared by malignant plasma cells and normal B cells may be involved in graft versus myeloma

SUMMARY Cytotoxic T cells play an important role in graft‐versus‐host‐disease (GvHD) and graft‐versus‐leukaemia/myeloma, which may occur in patients treated with an allogeneic stem cell transplantation (ASCT). Here, we describe the selection of a myeloma reactive CD4+ cytotoxic T cell‐line (CTL) and...

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Veröffentlicht in:	Clinical and experimental immunology 2003-02, Vol.131 (2), p.340-346
Hauptverfasser:	HOLLOWAY, P. A., KALDENHOVEN, N., KOK‐SCHOEMAKER, H. M., VAN KESSEL, B., VAN BLOKLAND, W. T. M., BLOEM, A. C., LOKHORST, H. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	allogeneic stem cell transplantation Antigens, Surface - analysis B-Lymphocytes - immunology Biological and medical sciences CD4-Positive T-Lymphocytes - immunology Cell Line Cell Transformation, Viral graft versus myeloma Graft vs Host Reaction - immunology Hematopoietic Stem Cell Transplantation Herpesvirus 4, Human Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunopathology Interferon-gamma - metabolism Lymphocyte Activation - immunology Male Medical sciences Middle Aged Multiple Myeloma - immunology myeloma Original Plasma Cells - immunology
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