Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

Fibroproliferative diseases, including the pulmonary fibroses, systemic sclerosis, liver cirrhosis, cardiovascular disease, progressive kidney disease, and macular degeneration, are a leading cause of morbidity and mortality and can affect all tissues and organ systems. Fibrotic tissue remodeling ca...

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Veröffentlicht in:	The Journal of clinical investigation 2007-03, Vol.117 (3), p.524-529
1. Verfasser:	Wynn, Thomas A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiotensin II - physiology Biomedical research Blood vessels Bone marrow Cardiovascular diseases Cell Proliferation Chemokines Chronic Disease Collagen Connective tissue Cytokines Disease Embryonic Stem Cells - transplantation Fibroblasts Fibroblasts - pathology Fibroblasts - physiology Fibrosis Fibrosis - etiology Fibrosis - immunology Fibrosis - therapy Growth factors Humans Infection - immunology Inflammation Kidney diseases Leukocytes Liver cirrhosis Macular degeneration Morbidity Mortality Neovascularization, Pathologic - immunology Neovascularization, Pathologic - metabolism Neutrophils Pulmonary fibrosis Review Series Scleroderma Scleroderma (Disease) Systemic scleroderma Transforming Growth Factor beta1 - physiology Wound Healing
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