Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27

Affected-sib-pair analyses were performed using 104 Caucasian families to map genes that predispose to insulin-dependent diabetes mellitus (IDDM). We have obtained linkage evidence for D6S446 (maximum lod score [MLS] = 2.8) and for D6S264 (MLS = 2.0) on 6q25-q27. Together with a previously reported...

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Veröffentlicht in:	American journal of human genetics 1995-10, Vol.57 (4), p.911-919
Hauptverfasser:	DE-FANG LUO, BUI, M. M, MUIR, A, MACLAREN, N. K, THOMSON, G, JIN-XIONG SHE
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosome Mapping Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 15 Chromosomes, Human, Pair 6 Diabetes Mellitus, Type 1 - genetics Diabetes. Impaired glucose tolerance DNA, Satellite - analysis Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Genetic Heterogeneity Genetic Linkage Genetic Predisposition to Disease Humans Lod Score Medical sciences Nuclear Family
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