Lipoprotein Electrophoretic Patterns, Serum Lipids, and Coronary Heart Disease
Lipoprotein electrophoresis was performed on serum from subjects with and without coronary heart disease, and the patterns compared with the serum concentrations of triglyceride and cholesterol. The beta- and pre-beta-lipoproteins, expressed as a percentage of the total lipoprotein, correlate strong...
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| Veröffentlicht in: | BMJ 1971-01, Vol.1 (5740), p.78-82 |
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| creator | Masarei, J. R. Summers, Margaret Curnow, D. H. Cullen, K. J. McCall, M. G. Stenhouse, N. S. Welborn, T. A. |
| description | Lipoprotein electrophoresis was performed on serum from subjects with and without coronary heart disease, and the patterns compared with the serum concentrations of triglyceride and cholesterol. The beta- and pre-beta-lipoproteins, expressed as a percentage of the total lipoprotein, correlate strongly with the cholesterol and triglyceride concentrations, respectively. The beta- and pre-beta-lipoprotein concentrations are even more strongly correlated with these lipid measurements. The lipoprotein pattern does not have greater discriminant value for coronary heart disease than does the triglyceride or cholesterol concentration. There would seem to be little justification for the use of lipoprotein electrophoresis in screening the general population for coronary heart disease. |
| doi_str_mv | 10.1136/bmj.1.5740.78 |
| format | Article |
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R. ; Summers, Margaret ; Curnow, D. H. ; Cullen, K. J. ; McCall, M. G. ; Stenhouse, N. S. ; Welborn, T. A.</creator><creatorcontrib>Masarei, J. R. ; Summers, Margaret ; Curnow, D. H. ; Cullen, K. J. ; McCall, M. G. ; Stenhouse, N. S. ; Welborn, T. A.</creatorcontrib><description>Lipoprotein electrophoresis was performed on serum from subjects with and without coronary heart disease, and the patterns compared with the serum concentrations of triglyceride and cholesterol. The beta- and pre-beta-lipoproteins, expressed as a percentage of the total lipoprotein, correlate strongly with the cholesterol and triglyceride concentrations, respectively. The beta- and pre-beta-lipoprotein concentrations are even more strongly correlated with these lipid measurements. The lipoprotein pattern does not have greater discriminant value for coronary heart disease than does the triglyceride or cholesterol concentration. There would seem to be little justification for the use of lipoprotein electrophoresis in screening the general population for coronary heart disease.</description><identifier>ISSN: 0007-1447</identifier><identifier>ISSN: 0959-8138</identifier><identifier>EISSN: 1468-5833</identifier><identifier>DOI: 10.1136/bmj.1.5740.78</identifier><identifier>PMID: 5539180</identifier><language>eng</language><publisher>England: British Medical Journal Publishing Group</publisher><subject>Adult ; Angina pectoris ; Blood ; Blood Protein Electrophoresis ; Cholesterol - blood ; Cholesterols ; Coronary artery disease ; Coronary Disease - blood ; Electrophoresis ; Female ; Humans ; LDL lipoproteins ; Lipids ; Lipids - blood ; Lipoproteins ; Lipoproteins - blood ; Male ; Middle Aged ; Myocardial infarction ; Papers and Originals ; Percentages ; Triglycerides - blood</subject><ispartof>BMJ, 1971-01, Vol.1 (5740), p.78-82</ispartof><rights>Copyright 1971 British Medical Journal</rights><rights>Copyright BMJ Publishing Group LTD Jan 9, 1971</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b503t-8c1a2956be1a771001e0698df84b4fef47a4f98563e7d19e6809c7cc764ee32c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/20263818$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/20263818$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,727,780,784,803,885,27922,27923,53789,53791,58015,58248</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5539180$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Masarei, J. R.</creatorcontrib><creatorcontrib>Summers, Margaret</creatorcontrib><creatorcontrib>Curnow, D. H.</creatorcontrib><creatorcontrib>Cullen, K. J.</creatorcontrib><creatorcontrib>McCall, M. G.</creatorcontrib><creatorcontrib>Stenhouse, N. S.</creatorcontrib><creatorcontrib>Welborn, T. A.</creatorcontrib><title>Lipoprotein Electrophoretic Patterns, Serum Lipids, and Coronary Heart Disease</title><title>BMJ</title><addtitle>Br Med J</addtitle><description>Lipoprotein electrophoresis was performed on serum from subjects with and without coronary heart disease, and the patterns compared with the serum concentrations of triglyceride and cholesterol. The beta- and pre-beta-lipoproteins, expressed as a percentage of the total lipoprotein, correlate strongly with the cholesterol and triglyceride concentrations, respectively. The beta- and pre-beta-lipoprotein concentrations are even more strongly correlated with these lipid measurements. The lipoprotein pattern does not have greater discriminant value for coronary heart disease than does the triglyceride or cholesterol concentration. There would seem to be little justification for the use of lipoprotein electrophoresis in screening the general population for coronary heart disease.</description><subject>Adult</subject><subject>Angina pectoris</subject><subject>Blood</subject><subject>Blood Protein Electrophoresis</subject><subject>Cholesterol - blood</subject><subject>Cholesterols</subject><subject>Coronary artery disease</subject><subject>Coronary Disease - blood</subject><subject>Electrophoresis</subject><subject>Female</subject><subject>Humans</subject><subject>LDL lipoproteins</subject><subject>Lipids</subject><subject>Lipids - blood</subject><subject>Lipoproteins</subject><subject>Lipoproteins - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial infarction</subject><subject>Papers and Originals</subject><subject>Percentages</subject><subject>Triglycerides - blood</subject><issn>0007-1447</issn><issn>0959-8138</issn><issn>1468-5833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kcGL1DAUxoMo67Du0aNQEMSDnU2aNEkvgs7sOsKwKq56DGn66mZsm5qkov_9pswwu3rw9Hh8P773PT6EnhK8JITy87rfLcmyFAwvhXyAFoRxmZeS0odogTEWOWFMPEZnIezSWlAhK85O0ElZ0opIvEBXWzu60bsIdsguOjDRu_HGeYjWZB91jOCH8Cr7DH7qs8TaJm16aLKV827Q_k-2Ae1jtrYBdIAn6FGruwBnh3mKvlxeXK82-fbDu_erN9u8LjGNuTREF1XJayBaCIIxAcwr2bSS1ayFlgnN2kqWnIJoSAVc4soIYwRnALQw9BS93vuOU91DY2CIXndq9LZPmZTTVv2tDPZGfXe_FBHprJTJ4MXBwLufE4SoehsMdJ0ewE1BSSx5gSlP4PN_wJ2b_JCeS16CFyXHdLbL95TxLgQP7TEKwWpuSqWmFFFzU0rM_LP7-Y_0oZc7fRei80e5wAWnkty7Z0OE30dd-x-KCypKdfV1pdbrDRHXn76pt4l_uefnGP-PdguDnrSE</recordid><startdate>19710109</startdate><enddate>19710109</enddate><creator>Masarei, J. 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| source | MEDLINE; JSTOR Archive Collection A-Z Listing; PubMed Central |
| subjects | Adult Angina pectoris Blood Blood Protein Electrophoresis Cholesterol - blood Cholesterols Coronary artery disease Coronary Disease - blood Electrophoresis Female Humans LDL lipoproteins Lipids Lipids - blood Lipoproteins Lipoproteins - blood Male Middle Aged Myocardial infarction Papers and Originals Percentages Triglycerides - blood |
| title | Lipoprotein Electrophoretic Patterns, Serum Lipids, and Coronary Heart Disease |
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