Pseudomonas cepacia: a new pathogen in patients with cystic fibrosis referred to a large centre in the United Kingdom
Pseudomonas cepacia infection has become increasingly common among patients with cystic fibrosis in North America. In a large cystic fibrosis centre in the United Kingdom 11 cases have been identified during the last six years, with a maximum prevalence of 7% in 1988. Three patients have died, two o...
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| Veröffentlicht in: | Archives of disease in childhood 1990-08, Vol.65 (8), p.874-877 |
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| container_title | Archives of disease in childhood |
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| creator | Simmonds, E J Conway, S P Ghoneim, A T Ross, H Littlewood, J M |
| description | Pseudomonas cepacia infection has become increasingly common among patients with cystic fibrosis in North America. In a large cystic fibrosis centre in the United Kingdom 11 cases have been identified during the last six years, with a maximum prevalence of 7% in 1988. Three patients have died, two of whom deteriorated rapidly shortly after acquisition of the organism despite intensive treatment with appropriate antibiotics. Analysis of possible causes of the increase in P cepacia infection suggested that neither patient to patient transmission nor the use of nebulised antibiotics was associated with an increased risk of infection. |
| doi_str_mv | 10.1136/adc.65.8.874 |
| format | Article |
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In a large cystic fibrosis centre in the United Kingdom 11 cases have been identified during the last six years, with a maximum prevalence of 7% in 1988. Three patients have died, two of whom deteriorated rapidly shortly after acquisition of the organism despite intensive treatment with appropriate antibiotics. Analysis of possible causes of the increase in P cepacia infection suggested that neither patient to patient transmission nor the use of nebulised antibiotics was associated with an increased risk of infection.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/adc.65.8.874</identifier><identifier>PMID: 2400225</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>Adolescent ; Adult ; Aminoglycosides ; Anti-Bacterial Agents - administration & dosage ; Antibiotics ; Care and treatment ; Child ; Child, Preschool ; Complications ; Cross Infection ; Cystic fibrosis ; Cystic Fibrosis - complications ; Drug resistance in microorganisms ; England - epidemiology ; Female ; Health aspects ; Health risks ; Humans ; Infant ; Male ; Microbial drug resistance ; Nebulizers and Vaporizers ; Pediatrics ; Pseudomonas cepacia ; Pseudomonas infections ; Pseudomonas Infections - epidemiology ; Pseudomonas Infections - etiology ; Retrospective Studies ; Risk Factors</subject><ispartof>Archives of disease in childhood, 1990-08, Vol.65 (8), p.874-877</ispartof><rights>Copyright BMJ Publishing Group LTD Aug 1990</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b538t-1a3b1c8b2616fecdfe33855ad9865b2165883eb0f4521e9cf89692683b6d7b7d3</citedby><cites>FETCH-LOGICAL-b538t-1a3b1c8b2616fecdfe33855ad9865b2165883eb0f4521e9cf89692683b6d7b7d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1792469/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1792469/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2400225$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Simmonds, E J</creatorcontrib><creatorcontrib>Conway, S P</creatorcontrib><creatorcontrib>Ghoneim, A T</creatorcontrib><creatorcontrib>Ross, H</creatorcontrib><creatorcontrib>Littlewood, J M</creatorcontrib><title>Pseudomonas cepacia: a new pathogen in patients with cystic fibrosis referred to a large centre in the United Kingdom</title><title>Archives of disease in childhood</title><addtitle>Arch Dis Child</addtitle><description>Pseudomonas cepacia infection has become increasingly common among patients with cystic fibrosis in North America. In a large cystic fibrosis centre in the United Kingdom 11 cases have been identified during the last six years, with a maximum prevalence of 7% in 1988. Three patients have died, two of whom deteriorated rapidly shortly after acquisition of the organism despite intensive treatment with appropriate antibiotics. Analysis of possible causes of the increase in P cepacia infection suggested that neither patient to patient transmission nor the use of nebulised antibiotics was associated with an increased risk of infection.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aminoglycosides</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Antibiotics</subject><subject>Care and treatment</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Complications</subject><subject>Cross Infection</subject><subject>Cystic fibrosis</subject><subject>Cystic Fibrosis - complications</subject><subject>Drug resistance in microorganisms</subject><subject>England - epidemiology</subject><subject>Female</subject><subject>Health aspects</subject><subject>Health risks</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Microbial drug resistance</subject><subject>Nebulizers and Vaporizers</subject><subject>Pediatrics</subject><subject>Pseudomonas cepacia</subject><subject>Pseudomonas infections</subject><subject>Pseudomonas Infections - 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In a large cystic fibrosis centre in the United Kingdom 11 cases have been identified during the last six years, with a maximum prevalence of 7% in 1988. Three patients have died, two of whom deteriorated rapidly shortly after acquisition of the organism despite intensive treatment with appropriate antibiotics. Analysis of possible causes of the increase in P cepacia infection suggested that neither patient to patient transmission nor the use of nebulised antibiotics was associated with an increased risk of infection.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</pub><pmid>2400225</pmid><doi>10.1136/adc.65.8.874</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Archives of disease in childhood, 1990-08, Vol.65 (8), p.874-877 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aminoglycosides Anti-Bacterial Agents - administration & dosage Antibiotics Care and treatment Child Child, Preschool Complications Cross Infection Cystic fibrosis Cystic Fibrosis - complications Drug resistance in microorganisms England - epidemiology Female Health aspects Health risks Humans Infant Male Microbial drug resistance Nebulizers and Vaporizers Pediatrics Pseudomonas cepacia Pseudomonas infections Pseudomonas Infections - epidemiology Pseudomonas Infections - etiology Retrospective Studies Risk Factors |
| title | Pseudomonas cepacia: a new pathogen in patients with cystic fibrosis referred to a large centre in the United Kingdom |
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