Expression and Effect of Inhibition of the Ubiquitin-Conjugating Enzyme E2C on Esophageal Adenocarcinoma1

Ubiquitin-dependent proteolysis of cyclins plays a critical role in cell cycle progression and tumorigenesis. We examined the expression of ubiquitin-conjugating enzyme E2C (UBE2C) during progression from Barrett's metaplasia to esophageal adenocarcinoma (EA) and the effects of targeting this e...

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Veröffentlicht in:Neoplasia (New York, N.Y.) N.Y.), 2006-12, Vol.8 (12), p.1062-1071
Hauptverfasser: Lin, Jules, Raoof, Duna A, Wang, Zhuwen, Lin, Mu-Yen, Thomas, Dafydd G, Greenson, Joel K, Giordano, Thomas J, Orringer, Mark B, Chang, Andrew C, Beer, David G, Lin, Lin
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Sprache:eng
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