Endocytosis and recycling of the complex between CD23 and HLA‐DR in human B cells

Summary The presentation of extremely low doses of antigen to T cells is enhanced by immunoglobulin E (IgE)‐dependent antigen focusing to CD23, the low‐affinity receptor for IgE, expressed on activated B cells. CD23 contains a C‐type lectin domain in its extracellular sequence and a targeting signal...

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Veröffentlicht in:	Immunology 2001-07, Vol.103 (3), p.319-331
Hauptverfasser:	Karagiannis, Sophia N., Warrack, John K., Jennings, Kevin H., Murdock, Paul R., Christie, Gary, Moulder, Kevin, Sutton, Brian J., Gould, Hannah J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - immunology Antigen-Antibody Complex - immunology B-Lymphocytes - immunology B-Lymphocytes - ultrastructure CD23 antigen Cell Culture Techniques Cytoplasmic Vesicles - immunology Electrophoresis, Polyacrylamide Gel Endocytosis - immunology Endosomes - immunology Endosomes - ultrastructure histocompatibility antigen HLA HLA-DR Antigens - immunology HLA-DR Antigens - metabolism Humans Immunoglobulin E - immunology Microscopy, Confocal Microscopy, Electron Original Receptors, IgE - immunology Receptors, IgE - metabolism
Online-Zugang:	Volltext
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