DS–Nh as an experimental model of atopic dermatitis induced by Staphylococcus aureus producing staphylococcal enterotoxin C

Summary DS–Nh mice raised under conventional conditions spontaneously develop dermatitis similar to human atopic dermatitis (AD), which is associated with staphylococcal infection. In the present study, we show that Staphylococcus aureus producing staphylococcus exotoxin C (SEC) was recovered from t...

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Veröffentlicht in:	Immunology 2003-04, Vol.108 (4), p.562-569
Hauptverfasser:	Yoshioka, T., Hikita, I., Matsutani, T., Yoshida, R., Asakawa, M., Toyosaki‐Maeda, T., Hirasawa, T., Suzuki, R., Arimura, A., Horikawa, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Bacterial - biosynthesis Antigens, Bacterial - immunology Cell Division - immunology Cells, Cultured Dermatitis, Atopic - immunology Dermatitis, Atopic - microbiology Dermatitis, Atopic - pathology Disease Models, Animal Enterotoxins - biosynthesis Enterotoxins - immunology Female Interferon-gamma - biosynthesis Interleukin-4 - biosynthesis Lymph Nodes - microbiology Male Mice Original Spleen - immunology Staphylococcal Infections - complications Staphylococcal Infections - immunology Staphylococcal Infections - pathology Staphylococcus aureus - immunology Staphylococcus aureus - isolation & purification Staphylococcus aureus - metabolism Superantigens - immunology
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