Interleukin‐3, but not granulocyte–macrophage colony‐stimulating factor and interleukin‐5, inhibits apoptosis of human basophils through phosphatidylinositol 3‐kinase: requirement of NF‐κB‐dependent and ‐independent pathways

Summary Basophils are key effector cells of allergic reactions. Although proinflammatory cytokines, such as interleukin (IL)‐3, granulocyte–macrophage colony‐stimulating factor (GM–CSF) and IL‐5, inhibit eosinophil apoptosis in vitro, little is known about basophil apoptosis, and the signalling mech...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Immunology 2002-11, Vol.107 (3), p.306-315
Hauptverfasser:	Zheng, Xueyan, Karsan, Aly, Duronio, Vincent, Chu, Fanny, Walker, David C., Bai, Tony R., Schellenberg, R. Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!