HeLa cells cocultured with peripheral blood lymphocytes acquire an immuno‐inhibitory phenotype through up‐regulation of indoleamine 2,3‐dioxygenase activity

Summary The mechanisms by which tumour cells escape recognition by the immune system or subvert antitumour effector responses remain poorly understood. In the course of investigating the potential of costimulatory signals in anticancer immunotherapy strategies, we have observed that HeLa cells (a hu...

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