Limited role of the Toll‐like receptor‐2 in resistance to Mycobacterium avium

Summary The role of the Toll‐like receptor (TLR)‐2 in the generation of protective immunity to Mycobacterium avium was evaluated using gene‐disrupted mice. TLR‐2−/− mice were more susceptible than wild‐type C57Bl/6 mice to M. avium strains that were able to proliferate in vivo before the development...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Immunology 2004-02, Vol.111 (2), p.179-185
Hauptverfasser:	Gomes, M. Salomé, Flórido, Manuela, Cordeiro, João V., Teixeira, C. Miguel, Takeuchi, Osamu, Akira, Shizuo, Appelberg, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals CD4-Positive T-Lymphocytes - immunology Genetic Predisposition to Disease Immunity, Cellular - genetics Interferon-gamma - biosynthesis Interleukin-12 - biosynthesis Macrophages - immunology Macrophages - microbiology Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Mice Mice, Inbred C57BL Mice, Mutant Strains Mycobacterium avium Mycobacterium avium - growth & development Original Receptors, Cell Surface - genetics Receptors, Cell Surface - immunology Spleen - immunology TLR2 protein Toll-Like Receptor 2 Toll-Like Receptors Tuberculosis - immunology Tuberculosis - prevention & control
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!