Long term prognosis of recurrent haematuria
A long term follow up study of 100 children referred with recurrent haematuria for at least one year to two regional paediatric nephrology units is described. The mean duration of follow up was 8.2 years. An adequate renal biopsy was obtained in 96 and eight cases of Alport's syndrome and 10 of...
Gespeichert in:
| Veröffentlicht in: | Archives of disease in childhood 1985-05, Vol.60 (5), p.420-425 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 425 |
|---|---|
| container_issue | 5 |
| container_start_page | 420 |
| container_title | Archives of disease in childhood |
| container_volume | 60 |
| creator | Miller, P F Speirs, N I Aparicio, S R Lendon, M Savage, J M Postlethwaite, R J Brocklebank, J T Houston, I B Meadow, S R |
| description | A long term follow up study of 100 children referred with recurrent haematuria for at least one year to two regional paediatric nephrology units is described. The mean duration of follow up was 8.2 years. An adequate renal biopsy was obtained in 96 and eight cases of Alport's syndrome and 10 of IgA nephropathy were diagnosed (20% and 26% respectively of the biopsies examined by electron microscopy and immunofluorescence). Five patients developed end stage renal failure and six hypertension requiring treatment, with the occurrence of these complications increasing progressively with increasing duration of follow up (1% at five years compared with 12% at 10 years). Adverse prognostic features were persistence of microscopic haematuria, proteinuria at presentation, and appreciable changes on renal biopsy. Eighty four patients had first degree relatives tested for haematuria; 30% of these families had another affected member. With long term follow up recurrent haematuria is associated with considerable morbidity and potential mortality. |
| doi_str_mv | 10.1136/adc.60.5.420 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1777302</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>76202875</sourcerecordid><originalsourceid>FETCH-LOGICAL-b4210-59a7f9da608f78b246d6d1eb40ccce57110afcb88d78883e3b514cce0b4730ae3</originalsourceid><addsrcrecordid>eNp90c1v0zAYBnBrAo1u7MYVKRJoHFjK64_YzgVpq2CbVDENAYddLMdxupQkLnYywX_Pi1pVwGGnHJ6fHj3OS8gLCnNKuXxnazeXMC_mgsEBmVEhdc5AiCdkBgA8L7XWz8hRSmsAyrTmh-RQAC0QzsjbZRhW2ehjn21iWA0htSkLTRa9m2L0w5jdW9_bcYqtfU6eNrZL_mT3PSZfP374srjKlzeX14vzZV4JRiEvSquasrYSdKN0xYSsZU19JcA55wtFKdjGVVrXCpdxzyucgglUQnGwnh-T99vezVT1vna4ItrObGLb2_jLBNuaf5OhvTer8GCoUtjAsOB0VxDDj8mn0fRtcr7r7ODDlIySDJhWBcJX_8F1mOKAj8MuWaqSSVaiOtsqF0NK0Tf7KRTMnxMYPIGRYAqDJ0D-8u_5e7z755i_3uU2Ods10Q6uTXtWMo6SI8u3rE2j_7mPbfxupOKqMJ--LczdxR1d0M_S3KJ_s_VVv3584G9D_6me</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1769792629</pqid></control><display><type>article</type><title>Long term prognosis of recurrent haematuria</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Miller, P F ; Speirs, N I ; Aparicio, S R ; Lendon, M ; Savage, J M ; Postlethwaite, R J ; Brocklebank, J T ; Houston, I B ; Meadow, S R</creator><creatorcontrib>Miller, P F ; Speirs, N I ; Aparicio, S R ; Lendon, M ; Savage, J M ; Postlethwaite, R J ; Brocklebank, J T ; Houston, I B ; Meadow, S R</creatorcontrib><description>A long term follow up study of 100 children referred with recurrent haematuria for at least one year to two regional paediatric nephrology units is described. The mean duration of follow up was 8.2 years. An adequate renal biopsy was obtained in 96 and eight cases of Alport's syndrome and 10 of IgA nephropathy were diagnosed (20% and 26% respectively of the biopsies examined by electron microscopy and immunofluorescence). Five patients developed end stage renal failure and six hypertension requiring treatment, with the occurrence of these complications increasing progressively with increasing duration of follow up (1% at five years compared with 12% at 10 years). Adverse prognostic features were persistence of microscopic haematuria, proteinuria at presentation, and appreciable changes on renal biopsy. Eighty four patients had first degree relatives tested for haematuria; 30% of these families had another affected member. With long term follow up recurrent haematuria is associated with considerable morbidity and potential mortality.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/adc.60.5.420</identifier><identifier>PMID: 4015146</identifier><identifier>CODEN: ADCHAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>Adolescent ; Biological and medical sciences ; Biopsy ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Hematuria - complications ; Hematuria - diagnosis ; Humans ; Hypertension ; Hypertension, Renal - etiology ; Infant ; Kidney - pathology ; Kidney Failure, Chronic - etiology ; Male ; Medical sciences ; Nephrology. Urinary tract diseases ; Prognosis ; Proteinuria - complications ; Recurrence ; Time Factors ; Urinary system involvement in other diseases. Miscellaneous ; Urinary tract. Prostate gland</subject><ispartof>Archives of disease in childhood, 1985-05, Vol.60 (5), p.420-425</ispartof><rights>1985 INIST-CNRS</rights><rights>Copyright BMJ Publishing Group LTD May 1985</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b4210-59a7f9da608f78b246d6d1eb40ccce57110afcb88d78883e3b514cce0b4730ae3</citedby><cites>FETCH-LOGICAL-b4210-59a7f9da608f78b246d6d1eb40ccce57110afcb88d78883e3b514cce0b4730ae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1777302/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1777302/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9234013$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4015146$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miller, P F</creatorcontrib><creatorcontrib>Speirs, N I</creatorcontrib><creatorcontrib>Aparicio, S R</creatorcontrib><creatorcontrib>Lendon, M</creatorcontrib><creatorcontrib>Savage, J M</creatorcontrib><creatorcontrib>Postlethwaite, R J</creatorcontrib><creatorcontrib>Brocklebank, J T</creatorcontrib><creatorcontrib>Houston, I B</creatorcontrib><creatorcontrib>Meadow, S R</creatorcontrib><title>Long term prognosis of recurrent haematuria</title><title>Archives of disease in childhood</title><addtitle>Arch Dis Child</addtitle><description>A long term follow up study of 100 children referred with recurrent haematuria for at least one year to two regional paediatric nephrology units is described. The mean duration of follow up was 8.2 years. An adequate renal biopsy was obtained in 96 and eight cases of Alport's syndrome and 10 of IgA nephropathy were diagnosed (20% and 26% respectively of the biopsies examined by electron microscopy and immunofluorescence). Five patients developed end stage renal failure and six hypertension requiring treatment, with the occurrence of these complications increasing progressively with increasing duration of follow up (1% at five years compared with 12% at 10 years). Adverse prognostic features were persistence of microscopic haematuria, proteinuria at presentation, and appreciable changes on renal biopsy. Eighty four patients had first degree relatives tested for haematuria; 30% of these families had another affected member. With long term follow up recurrent haematuria is associated with considerable morbidity and potential mortality.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hematuria - complications</subject><subject>Hematuria - diagnosis</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypertension, Renal - etiology</subject><subject>Infant</subject><subject>Kidney - pathology</subject><subject>Kidney Failure, Chronic - etiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Prognosis</subject><subject>Proteinuria - complications</subject><subject>Recurrence</subject><subject>Time Factors</subject><subject>Urinary system involvement in other diseases. Miscellaneous</subject><subject>Urinary tract. Prostate gland</subject><issn>0003-9888</issn><issn>1468-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp90c1v0zAYBnBrAo1u7MYVKRJoHFjK64_YzgVpq2CbVDENAYddLMdxupQkLnYywX_Pi1pVwGGnHJ6fHj3OS8gLCnNKuXxnazeXMC_mgsEBmVEhdc5AiCdkBgA8L7XWz8hRSmsAyrTmh-RQAC0QzsjbZRhW2ehjn21iWA0htSkLTRa9m2L0w5jdW9_bcYqtfU6eNrZL_mT3PSZfP374srjKlzeX14vzZV4JRiEvSquasrYSdKN0xYSsZU19JcA55wtFKdjGVVrXCpdxzyucgglUQnGwnh-T99vezVT1vna4ItrObGLb2_jLBNuaf5OhvTer8GCoUtjAsOB0VxDDj8mn0fRtcr7r7ODDlIySDJhWBcJX_8F1mOKAj8MuWaqSSVaiOtsqF0NK0Tf7KRTMnxMYPIGRYAqDJ0D-8u_5e7z755i_3uU2Ods10Q6uTXtWMo6SI8u3rE2j_7mPbfxupOKqMJ--LczdxR1d0M_S3KJ_s_VVv3584G9D_6me</recordid><startdate>19850501</startdate><enddate>19850501</enddate><creator>Miller, P F</creator><creator>Speirs, N I</creator><creator>Aparicio, S R</creator><creator>Lendon, M</creator><creator>Savage, J M</creator><creator>Postlethwaite, R J</creator><creator>Brocklebank, J T</creator><creator>Houston, I B</creator><creator>Meadow, S R</creator><general>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8A4</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19850501</creationdate><title>Long term prognosis of recurrent haematuria</title><author>Miller, P F ; Speirs, N I ; Aparicio, S R ; Lendon, M ; Savage, J M ; Postlethwaite, R J ; Brocklebank, J T ; Houston, I B ; Meadow, S R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b4210-59a7f9da608f78b246d6d1eb40ccce57110afcb88d78883e3b514cce0b4730ae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hematuria - complications</topic><topic>Hematuria - diagnosis</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hypertension, Renal - etiology</topic><topic>Infant</topic><topic>Kidney - pathology</topic><topic>Kidney Failure, Chronic - etiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Prognosis</topic><topic>Proteinuria - complications</topic><topic>Recurrence</topic><topic>Time Factors</topic><topic>Urinary system involvement in other diseases. Miscellaneous</topic><topic>Urinary tract. Prostate gland</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miller, P F</creatorcontrib><creatorcontrib>Speirs, N I</creatorcontrib><creatorcontrib>Aparicio, S R</creatorcontrib><creatorcontrib>Lendon, M</creatorcontrib><creatorcontrib>Savage, J M</creatorcontrib><creatorcontrib>Postlethwaite, R J</creatorcontrib><creatorcontrib>Brocklebank, J T</creatorcontrib><creatorcontrib>Houston, I B</creatorcontrib><creatorcontrib>Meadow, S R</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Education Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Education Periodicals</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Education Database</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Archives of disease in childhood</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miller, P F</au><au>Speirs, N I</au><au>Aparicio, S R</au><au>Lendon, M</au><au>Savage, J M</au><au>Postlethwaite, R J</au><au>Brocklebank, J T</au><au>Houston, I B</au><au>Meadow, S R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long term prognosis of recurrent haematuria</atitle><jtitle>Archives of disease in childhood</jtitle><addtitle>Arch Dis Child</addtitle><date>1985-05-01</date><risdate>1985</risdate><volume>60</volume><issue>5</issue><spage>420</spage><epage>425</epage><pages>420-425</pages><issn>0003-9888</issn><eissn>1468-2044</eissn><coden>ADCHAK</coden><abstract>A long term follow up study of 100 children referred with recurrent haematuria for at least one year to two regional paediatric nephrology units is described. The mean duration of follow up was 8.2 years. An adequate renal biopsy was obtained in 96 and eight cases of Alport's syndrome and 10 of IgA nephropathy were diagnosed (20% and 26% respectively of the biopsies examined by electron microscopy and immunofluorescence). Five patients developed end stage renal failure and six hypertension requiring treatment, with the occurrence of these complications increasing progressively with increasing duration of follow up (1% at five years compared with 12% at 10 years). Adverse prognostic features were persistence of microscopic haematuria, proteinuria at presentation, and appreciable changes on renal biopsy. Eighty four patients had first degree relatives tested for haematuria; 30% of these families had another affected member. With long term follow up recurrent haematuria is associated with considerable morbidity and potential mortality.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</pub><pmid>4015146</pmid><doi>10.1136/adc.60.5.420</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-9888 |
| ispartof | Archives of disease in childhood, 1985-05, Vol.60 (5), p.420-425 |
| issn | 0003-9888 1468-2044 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1777302 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adolescent Biological and medical sciences Biopsy Child Child, Preschool Female Follow-Up Studies Hematuria - complications Hematuria - diagnosis Humans Hypertension Hypertension, Renal - etiology Infant Kidney - pathology Kidney Failure, Chronic - etiology Male Medical sciences Nephrology. Urinary tract diseases Prognosis Proteinuria - complications Recurrence Time Factors Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland |
| title | Long term prognosis of recurrent haematuria |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T10%3A30%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Long%20term%20prognosis%20of%20recurrent%20haematuria&rft.jtitle=Archives%20of%20disease%20in%20childhood&rft.au=Miller,%20P%20F&rft.date=1985-05-01&rft.volume=60&rft.issue=5&rft.spage=420&rft.epage=425&rft.pages=420-425&rft.issn=0003-9888&rft.eissn=1468-2044&rft.coden=ADCHAK&rft_id=info:doi/10.1136/adc.60.5.420&rft_dat=%3Cproquest_pubme%3E76202875%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1769792629&rft_id=info:pmid/4015146&rfr_iscdi=true |