Effect of a sulphated glycopeptide on rat gastric acid secretion stimulated by histamine, bethanechol, pentagastrin and dibutyryl cyclic AMP

The antisecretory activity of a semisynthetic sulphated glycopeptide (GLPS) was studied in rats in which the secretion rates of gastric acid were detennined on the perfused stomach preparation. GLPS at 1 mg/kg i.v. reduced the hypersecretory effect of dibutyryl cyclic AMP, histamine, pentagastrin, b...

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Veröffentlicht in:	British journal of pharmacology 1973-07, Vol.48 (3), p.550-552
Hauptverfasser:	Niada, R., Prino, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bethanechol Compounds - antagonists & inhibitors Cyclic AMP - antagonists & inhibitors Gastric Juice - drug effects Gastric Juice - metabolism Glycopeptides - pharmacology Histamine Antagonists Male Pentagastrin - antagonists & inhibitors Rats Short Communications Theophylline - pharmacology
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