Cellular detection of sst2A receptors in human gastrointestinal tissue

Background and aim: Many neuroendocrine gastrointestinal tumours express receptors for the regulatory peptide somatostatin. Among the five existing somatostatin receptor (sst) subtypes, sst2A is the most frequently expressed in these tumours. However, little information is available about the cellul...

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Veröffentlicht in:	Gut 2004-10, Vol.53 (10), p.1431-1436
Hauptverfasser:	Gugger, M, Waser, B, Kappeler, A, Schonbrunn, A, Reubi, J C
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites CgA chromograninA ECL enterochromaffin-like Enteroendocrine Cells - metabolism epithelium Gastric Mucosa - metabolism HDC histidine decarboxylase Humans Immunoenzyme Techniques Intestinal Mucosa - metabolism Intestine, Small - metabolism Localization neuroendocrine tumours non-neoplastic gastrointestinal tissue physiology Proteins Pyloric Antrum - metabolism Receptors, Somatostatin - metabolism Small Intestine Somatostatin - physiology somatostatin receptor sst Studies TBS Tris buffered saline Tumors
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