Bone density loss in Crohn’s disease: role of TNF and potential for prevention by bupropion

The subject of bone mineral density loss in CD has been recently reviewed; tumour necrosis factor α (TNF-α) is suspected of being an important mediator of this loss. 1, 2 Evidence has been published for localised overproduction of TNF-α being largely responsible for the bone loss seen in rheumato...

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Veröffentlicht in:	Gut 2004-07, Vol.53 (7), p.1056-1056
Hauptverfasser:	Kast, R E, Altschuler, E L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressive Agents, Second-Generation - therapeutic use Bone density Bone Density - drug effects bupropion Bupropion - therapeutic use Crohn Disease - complications Crohn's disease Humans Letter osteoporosis Osteoporosis - etiology Psoriasis Tumor Necrosis Factor-alpha - physiology Tumor necrosis factor-TNF tumour necrosis factor
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