TLRs and NODs mRNA expression pattern in healthy mouse eye

Aims: To look for TLR and NOD mRNA expression in the healthy eye and in other immune privileged and non-immune privileged mouse organs. Methods: Semiquantitative RT-PCR was performed to look for TLR1–9 and NOD1 and NOD2 mRNA expressions in the whole eye, in the anterior (AP) and posterior (PP) porti...

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Veröffentlicht in:	British journal of ophthalmology 2005-07, Vol.89 (7), p.904-910
Hauptverfasser:	Rodríguez-Martínez, S, Cancino-Díaz, M E, Jiménez-Zamudio, L, García-Latorre, E, Cancino-Díaz, J C
Format:	Artikel
Sprache:	eng
Schlagworte:	ACAID Adaptor Proteins, Signal Transducing - analysis Animals anterior chamber immune deviation anterior portion antigen presenting cells APC Biological and medical sciences Cells, Cultured corneal fibroblast corneal fibroblasts eye Eye - chemistry Eye - immunology Eye Proteins - analysis Eye Proteins - immunology Female Fibroblasts Fibroblasts - chemistry Fibroblasts - immunology Gene expression Herpes viruses interleukin Intracellular Signaling Peptides and Proteins - analysis Laboratory Science - Extended Reports lipopolysaccharide LPS Male Medical sciences Membrane Glycoproteins - analysis Membrane Glycoproteins - immunology Mice Mice, Inbred BALB C Mice, Inbred C57BL Miscellaneous mouse model NOD Nod1 Signaling Adaptor Protein Nod2 Signaling Adaptor Protein nucleotide binding oligomerisation domain nucleotide binding oligomerisation domain protein Ophthalmology PAMPs pathogen associated molecular patterns pattern recognition receptors posterior portion Proteins PRRs Receptors, Cell Surface - analysis Receptors, Cell Surface - immunology reverse transcriptase polymerase chain reaction Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - analysis Rodents RT-PCR Signal transduction TGF TIR TLR/IL-1 receptor TLRs Toll-Like Receptor 1 Toll-Like Receptor 8 Toll-Like Receptors transforming growth factor
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