Acquired ocular toxoplasmosis in pregnancy

Serological testing revealed antibodies to Toxoplasma gondii at a titre of 1/4096 (2000 IU/ml) using the dye test and a toxoplasma IgM enzyme linked immunosorbent assay (ELISA) on the patient's peripheral blood was positive. Comment In the United Kingdom ocular toxoplasmosis is normally thought to occur through the congenital route, although recent evidence suggests that we may be underestimating the amount of acquired disease. 1- 6 Overall, about 40% of primary maternal infections lead to congenital infection of children, 7 with a transplacental transmission rate of T gondii reported to be 3% in the first trimester, 22% in the second, and 63% in the third. 8 In our case the features supporting an acquired aetiology included lack retinal scars from previous infection, and the positive IgM serology and IgG avidity results. 9 Sera taken early in infection (